Generic Niftran™®: Nitrofurantoin
Nitrofurantoin is the chemical name of the active ingredient in Niftran™®
Tablet Chemical Name: Nitrofurantoin.
Other name brands for this medication
Macrobid, Macrodantin, Furadantin
Possible Uses of Niftran: This medication is used to treat or prevent certain urinary tract infections. This medication is an antibiotic that works by stopping the growth of bacteria. It will not work for viral infections (e.g., common cold, flu). Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness. Nitrofurantoin should not be used in children less than one month of age due to the risk of a certain blood problem (hemolytic anemia).
Before using Niftran: Before taking nitrofurantoin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
How to take Niftran: Take this medication by mouth, with food or milk, as directed by your doctor. This medication is usually taken four times daily to treat an infection or once daily at bedtime to prevent infections. Swallow the medication whole. Avoid using magnesium trisilicate-containing antacids while taking this medication. Magnesium trisilicate-containing antacids bind with nitrofurantoin, preventing its full absorption.
Dosage and duration is based on your medical condition and response to therapy. For children, the dosage is also based on body weight. Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, take this medication at evenly spaced intervals.
When taking this medication to prevent infection, take it exactly as directed by your doctor. Do not skip doses or stop taking it without your doctor's approval. Inform your doctor if you notice signs of a new urinary tract infection (e.g., pain while you are urinating).
If you are taking this medication to treat an infection, continue to take this medication until the full-prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a relapse of the infection. Inform your doctor if your condition persists or worsens.
Precautions When Using Niftran: This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: little or no urine output (oliguria or anuria), severe kidney disease, certain genetic conditions (glucose-6-phosphate dehydrogenase deficiency), a history of liver problems due to nitrofurantoin use in the past.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: certain blood disorders (e.g., anemia), kidney or liver problems, lung diseases, certain nerve problems (peripheral neuropathy), certain eye diseases (optic neuritis), diabetes, untreated mineral imbalance, vitamin B deficiency. Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore, older adults may be at a greater risk for side effects while using this drug, especially nerve, liver or lung problems (see Side Effects section).
This medication should be used only when clearly needed during pregnancy. This medication should not be taken if you are at term (weeks 38-42 of pregnancy), near or at the time of delivery due to possible harm to the newborn, such as a certain blood problem (hemolytic anemia). Discuss the risks and benefits with your doctor. This medication passes into breast milk and may have undesirable effects on nursing infants less than one month old and infants with a certain genetic condition (G-6-PD deficiency). Consult your doctor before breast-feeding.
Side Effects of Niftran: Nausea, vomiting, loss of appetite, or headache may occur. Take this medication with food to help minimize nausea. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. This medication may cause your urine to turn dark yellow or brown in color. This effect is harmless and will disappear when the medication is stopped. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
This drug may infrequently cause very serious (rarely fatal) lung problems. Lung problems may occur soon after starting the medicine or after long-term use. Seek immediate medical attention if you notice any of the following unlikely but very serious side effects: chest pain, shortness of breath, unusual/persistent cough. Tell your doctor immediately if any of these rare but very serious side effects occur: new signs of infection (e.g., fever, persistent sore throat), easy bruising/bleeding, mental/mood changes, persistent or severe headaches, vision changes.
This drug may rarely cause serious (possibly fatal) liver disease, blood or nerve problems. Tell your doctor immediately if you notice any of the following rare but very serious side effects: persistent nausea/vomiting, dark urine, yellowing of eyes/skin, unusual/persistent fatigue, fast/pounding heartbeat, numbness/tingling of the arms/legs, muscle weakness. This medication may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a type of resistant bacteria. This condition may occur during treatment or weeks to months after treatment has stopped. Do not use anti-diarrhea products or narcotic pain medications if you have any of the following symptoms because these products may make them worse. Tell your doctor immediately if you develop: persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool.
Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection (e.g., oral or vaginal fungal infection). Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms. A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Drug Interactions of Niftran: Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: probenecid, sulfinpyrazone.
Although most antibiotics probably do not affect hormonal birth control such as pills, patch, or ring, some antibiotics may decrease their effectiveness. This could cause pregnancy. Examples include rifamycins such as rifampin or rifabutin. Be sure to ask your doctor or pharmacist if you should use additional reliable birth control methods while using this antibiotic.
This drug can affect the results of certain urine glucose tests (cupric sulfate-type). Make sure laboratory personnel and your doctors know you use this drug. This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
Missed dose of Niftran: If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Overdose of Niftran: If overdose is suspected, contact a poison control center or emergency room immediately.
Storage of Niftran: Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.
Other Information of Niftran: DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.