Generic Sporanox™®: Itraconazole
Itraconazole is the chemical name of the active ingredient in Sporanox™®
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Tablet Chemical Name: Itraconazole.
Other name brands for this medication
Possible Uses of Sporanox: Itraconazole is an azole antifungal medication used to treat a variety of fungal infections.
OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. This drug may also be used to prevent certain fungal infections in patients with HIV.
Before using Sporanox: Before taking itraconazole, tell your doctor or pharmacist if you are allergic to it; or to other azole antifungals (e.g., ketoconazole); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
How to take Sporanox: Read the Patient Information Leaflet provided by your pharmacist before you start taking itraconazole and each time you get a refill. If you have any questions, consult your doctor or pharmacist.
Take this medication by mouth with a full meal, usually once or twice daily or as directed by your doctor. The capsules must be swallowed whole. The dosage is based on your medical condition and response to therapy. Take this medication exactly as prescribed by your doctor. Some conditions may require you to take this medication for 1 week each month until therapy is completed.
This medication works best when the amount of medicine in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals. If you are taking this medication on a schedule other than every day (e.g., 1 week every month), it may help to mark your calendar with a reminder.
You may need to take this medication for several months to treat the infection. Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear. Stopping the medication too early may result in a return of the infection.
Take itraconazole 2 hours before or 1 hour after antacids. Antacids may decrease the absorption of this medication. Also, take this medication with a cola drink if you have decreased or no stomach acid (e.g., achlorhydria) or if you take drugs that decrease stomach acid (e.g., H2 blockers such as ranitidine, proton pump inhibitors such as omeprazole). Consult your doctor or pharmacist for more details.
The tablet/capsule and solution forms of this medication deliver different amounts of medication and may be used for different purposes. Do not switch dosage forms without your doctor's permission and directions. Inform your doctor if your condition persists or worsens.
Precautions When Using Sporanox: Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease (or history of liver disease with other drugs), kidney disease, heart disease (e.g., coronary artery disease, heart valve disease, congestive heart failure), severe lung disease (e.g., chronic obstructive pulmonary disease-COPD), high blood pressure, decreased or no stomach acid (e.g., achlorhydria).
This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages since they can increase the effects of dizziness and also increase the risk of serious liver problems.
Older adults may be at greater risk for hearing loss while using this drug.
During pregnancy, this medication should be used only when clearly needed. It may harm an unborn baby. Discuss the risks and benefits with your doctor. This medication should not be used to treat fungal nail infections if you are pregnant or could become pregnant during treatment. Women of childbearing age should start this medication 2 to 3 days after the start of their periods to make sure that they are not pregnant. Discuss the use of reliable forms of birth control (such as condoms and birth control pills) while taking this medication and for 2 months after stopping it. Itraconazole passes into breast milk. Consult your doctor before breast-feeding.
Side Effects of Sporanox: Nausea/vomiting, diarrhea, gas, headache, dizziness, or stomach upset may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor immediately if any of these unlikely but serious side effects occur: signs of infection (e.g., fever, persistent sore throat), trouble breathing, unusual tiredness, swelling ankles/feet, burning/painful/frequent urination, decreased sexual interest/ability, hair loss, muscle cramps/pain, weakness, fast/irregular heartbeat, mental/mood changes (e.g., depression), enlarged breasts in men, ringing in the ears, temporary or permanent hearing loss.
Tell your doctor immediately if any of these rare but very serious side effects occur: numbness/tingling of the hands/feet. Itraconazole has rarely caused very serious (possibly fatal) liver disease. If you notice any of the following highly unlikely but very serious side effects, stop taking itraconazole and tell your doctor immediately: yellowing eyes/skin, dark urine, persistent nausea/vomiting, stomach/abdominal pain.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
Itraconazole can commonly cause a mild rash that is usually not serious. However, you may not be able to tell it apart from a rare rash that could be a sign of a severe allergic reaction. Therefore, seek immediate medical attention if you develop any rash. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Drug Interactions of Sporanox: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Some products that may interact with this drug include: alfuzosin, certain benzodiazepines (such as oral midazolam, triazolam, alprazolam, estazolam), conivaptan, eletriptan, eplerenone, ivabradine, lurasidone, ranolazine, , amiodarone, calcium channel blockers (such as verapamil, nifedipine), colchicine.
This drug can slow down the removal of other drugs from your body, which may affect how they work. Examples of affected drugs include certain antiarrhythmic medications (such as digoxin), certain chemotherapy drugs (such as busulfan, docetaxel, vinblastine, sunitinib, lapatinib, dasatinib), certain benzodiazepines (such as diazepam, injectable midazolam), certain immunosuppressants (such as tacrolimus, cyclosporine, sirolimus), certain "statin" drugs (such as atorvastatin), HIV protease inhibitors (such as indinavir, ritonavir, saquinavir), alfentanil, fentanyl, buspirone, repaglinide, certain drugs to treat erectile dysfunction-ED or pulmonary hypertension (such as , ), trimetrexate, aripiprazole, trazodone, tolterodine, "blood thinners" (such as warfarin), cilostazol, among others.
Other medications can affect the removal of itraconazole from your body, which may affect how itraconazole works. Examples include cimetidine, isoniazid, macrolide antibiotics (such as erythromycin), rifamycins (such as rifabutin), nevirapine, certain drugs used to treat seizures (such as carbamazepine, phenytoin), among others.
Missed dose of Sporanox: If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Overdose of Sporanox: If overdose is suspected, contact a poison control center or emergency room immediately.
Storage of Sporanox: Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.
Other Information of Sporanox: DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.
COST OF Sporanox : The lowest MyGenericPharmacy.com price for the most common version of Sporanox (Itraconazole) is around $1.12, 57% off the average online retailing price of $78.60.