Generic Tasigna® : Nilotinib
Medication information about generic Tasigna
Important information about usage, risks and possible side-effects..
Generic Buy Tasigna™ 200 mg (28 Pills) for Cancer
Buy online Generic Tasigna™ 200 mg (28 Pills) for Tasigna Cost, Price $588.00 at 51% Discount.
Other name brands for this medication
Tasigna, Nelova, Nilocap, Knilonat
Possible Uses of Nilotinib :
Nilotinib is used to treat a certain type of blood cancer (chronic myelogenous leukemia-CML). It works by slowing or stopping the growth of cancer cells.
Before using Nilotinib :
Before taking nilotinib, tell your doctor or pharmacist if you are allergic to it; or to lactose/galactose; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
How to take Nilotinib :
Read the Medication Guide provided by your pharmacist before you start using nilotinib and each time you get a refill. If you have any questions, consult your doctor or pharmacist.
Take this medication by mouth on an empty stomach as directed by your doctor, usually twice daily (about 12 hours apart). Swallow the capsule whole with water. Do not open, break, or chew the capsules. Do not eat any food for at least 2 hours before or for 1 hour after taking your dose. Taking this medication with food can increase the amount of drug in your body and increase the risk of serious side effects. If unable to swallow the capsules, the capsules may be opened and the contents sprinkled in 1 teaspoon of applesauce. This mixture should be swallowed right away (within 15 minutes). Use only 1 teaspoon of applesauce. Do not sprinkle the contents onto other types of food.
Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. Grapefruit can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details.
Drink plenty of fluids during treatment with this medication, unless otherwise directed by your doctor.
If you are also taking an antacid, take it 2 hours before or after nilotinib. If you are also taking an H2 blocker (such as cimetidine, famotidine), take it 10 hours before or 2 hours after nilotinib.
The dosage is based on your medical condition, response to treatment, laboratory tests, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Children's dosage is also based on body size.
Do not increase your dose or take this medication more often than prescribed. Your condition will not improve any faster, and the risk of serious side effects may be increased.
Since this drug can be absorbed through the skin and lungs, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the contents of the capsules.
Precautions When Using Nilotinib :
Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, pancreatitis, heart disease (such as coronary artery disease, chest pain, heart attack), high blood pressure, high cholesterol, diabetes, stroke (including "mini-strokes" or transient ischemic attacks), blood circulation disease (peripheral arterial disease), blood vessel disease (hardening of the arteries/atherosclerosis), stomach surgery (such as gastrectomy).
Nilotinib may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.
The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using nilotinib, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).
Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using nilotinib safely.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Nilotinib can make you more likely to get infections or may worsen any current infections. Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu). Consult your doctor if you have been exposed to an infection or for more details.
Tell your health care professional that you are using nilotinib before having any immunizations/vaccinations. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose).
To lower the chance of getting cut, bruised, or injured, use caution with sharp objects like razors and nail cutters, and avoid activities such as contact sports.
Children may be more sensitive to the side effects of this drug, especially liver disease, and slowed growth and development. Consult the doctor or pharmacist for more details. See the doctor regularly so your child's liver function, height, weight, and development can be checked.
Older adults may be more sensitive to the side effects of this drug, especially QT prolongation (see above).
Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while using nilotinib. Nilotinib may harm an unborn baby. Ask about reliable forms of birth control while using this medication and for 14 days after stopping treatment. If you become pregnant, talk to your doctor right away about the risks and benefits of this medication.
It is not known whether this drug passes into breast milk. Because of the possible risk to the infant, breast-feeding while using this drug and for 14 days after stopping treatment is not recommended. Consult your doctor before breast-feeding.
Side Effects of Nilotinib :
Nausea, vomiting, headache, tiredness, constipation, and diarrhea may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
People using this medication may have serious side effects. However, you have been prescribed this drug because your doctor has judged that the benefit to you is greater than the risk of side effects. Careful monitoring by your doctor may decrease your risk.
This medication decreases bone marrow function, an effect that may lead to a low number of blood cells such as red cells, white cells, and platelets. This effect can cause anemia, decrease your body's ability to fight an infection, or cause easy bruising/bleeding. Tell your doctor right away if you develop any of the following serious symptoms: severe tiredness, pale skin, signs of infection (such as sore throat that doesn't go away, fever, chills), easy bruising/bleeding (such as bloody/black stool, bloody/pink urine).
Nilotinib sometimes causes side effects due to the rapid destruction of cancer cells (tumor lysis syndrome). To lower your risk, your doctor may add a medication and tell you to drink plenty of fluids. Tell your doctor right away if you have symptoms such as: low back/side pain (flank pain), signs of kidney problems (such as painful urination, change in the amount of urine), muscle spasms/weakness.
Tell your doctor right away if you have any serious side effects, including: severe stomach/abdominal pain, toe/joint pain, swelling hands/ankles/feet, unusual/rapid weight gain, symptoms of high blood sugar (such as increased thirst/urination), signs of liver disease (such as nausea/vomiting that doesn't stop, stomach/abdominal pain, yellowing eyes/skin, dark urine).
Get medical help right away if you have any very serious side effects, including: fast/pounding/irregular heartbeat, severe dizziness, fainting, seizures, signs of a heart attack (such as chest/jaw/left arm pain, shortness of breath, unusual sweating), signs of a stroke (such as weakness on one side of the body, trouble speaking, sudden vision changes, confusion), signs of bleeding in the brain (such as sudden severe headache, sudden vision changes, confusion, loss of consciousness), signs of blood circulation disease (such as numbness/pain in the legs, leg pain with physical activity, decrease in walking distance).
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Drug Interactions of Nilotinib :
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Some products that may interact with this drug include: antacids, flibanserin, H2 blockers (such as cimetidine/famotidine), proton pump inhibitors (such as omeprazole).
Other medications can affect the removal of nilotinib from your body, which may affect how nilotinib works. Examples include azole antifungals (such as itraconazole, ketoconazole), HIV protease inhibitors (such as ritonavir), macrolide antibiotics (such as clarithromycin), rifamycins (such as rifabutin), St. John's wort, drugs used to treat seizures (such as carbamazepine, phenytoin), among others.
Many drugs besides nilotinib may affect the heart rhythm (QT prolongation), including amiodarone, dofetilide, pimozide, procainamide, quinidine, sotalol, macrolide antibiotics (such as erythromycin), among others.
Missed dose of Nilotinib :
If you miss a dose, take it as soon as you remember, but do not take if it is less than 2 hours before or 1 hour after a meal. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Over dose of Nilotinib :
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call a poison control center right away.
Storage of Nilotinib :
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Other Information of Nilotinib :
FOR BEST RESULTS, this medicine should be used along with exercise, a low-cholesterol/low-fat diet, and a weight loss program if you are overweight. FOLLOW THE DIETARY PLAN provided by your doctor. DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children and pets. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.
Cost Of Nilotinib : The lowest MyGenericPharmacy.com price for the most common version of Tasigna (Nilotinib) is around $21.00, 51% off the average online retailing price of $1204.00.
MISSPELLINGS OF NILOTINIB :
Tasignna, Tasigina, Tasinga, Tasignah, Tasignaax, Tasiggna, Tasignaaz, Tasignea, Tasignna, Tasignaaa, Tasigana, Tasignnaah, Tasignae, Tasiginaa, Tasiginaax,
Tazigna, Tasina, Tasinga, Tasynha, Nilotinibb, Nilotnib, Nilotiniib, Nilotinibx, Nilotinibz, Nilotineb, Nilotinip, Nilotinnib, Nilotiniv, Nilotinob, Nilotanib, Nilotnibb, Nilotonib, Nilotinieb, Nilotinibe, Nilotinibe, Nilotib, Nilotinibbe, Nilothinib,
Nilotenib, Nilotynib.
Generic Tasigna® : Nilotinib
Medication information about generic Tasigna
Important information about usage, risks and possible side-effects..
Generic Buy Tasigna™ 200 mg (28 Pills) for Cancer
Buy online Generic Tasigna™ 200 mg (28 Pills) for Tasigna Cost, Price $588.00 at 51% Discount.
Other name brands for this medication
Tasigna, Nelova, Nilocap, Knilonat
Possible Uses of Nilotinib :
Nilotinib is used to treat a certain type of blood cancer (chronic myelogenous leukemia-CML). It works by slowing or stopping the growth of cancer cells.
Before using Nilotinib :
Before taking nilotinib, tell your doctor or pharmacist if you are allergic to it; or to lactose/galactose; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
How to take Nilotinib :
Read the Medication Guide provided by your pharmacist before you start using nilotinib and each time you get a refill. If you have any questions, consult your doctor or pharmacist.
Take this medication by mouth on an empty stomach as directed by your doctor, usually twice daily (about 12 hours apart). Swallow the capsule whole with water. Do not open, break, or chew the capsules. Do not eat any food for at least 2 hours before or for 1 hour after taking your dose. Taking this medication with food can increase the amount of drug in your body and increase the risk of serious side effects. If unable to swallow the capsules, the capsules may be opened and the contents sprinkled in 1 teaspoon of applesauce. This mixture should be swallowed right away (within 15 minutes). Use only 1 teaspoon of applesauce. Do not sprinkle the contents onto other types of food.
Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. Grapefruit can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details.
Drink plenty of fluids during treatment with this medication, unless otherwise directed by your doctor.
If you are also taking an antacid, take it 2 hours before or after nilotinib. If you are also taking an H2 blocker (such as cimetidine, famotidine), take it 10 hours before or 2 hours after nilotinib.
The dosage is based on your medical condition, response to treatment, laboratory tests, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Children's dosage is also based on body size.
Do not increase your dose or take this medication more often than prescribed. Your condition will not improve any faster, and the risk of serious side effects may be increased.
Since this drug can be absorbed through the skin and lungs, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the contents of the capsules.
Precautions When Using Nilotinib :
Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, pancreatitis, heart disease (such as coronary artery disease, chest pain, heart attack), high blood pressure, high cholesterol, diabetes, stroke (including "mini-strokes" or transient ischemic attacks), blood circulation disease (peripheral arterial disease), blood vessel disease (hardening of the arteries/atherosclerosis), stomach surgery (such as gastrectomy).
Nilotinib may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.
The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using nilotinib, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).
Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using nilotinib safely.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Nilotinib can make you more likely to get infections or may worsen any current infections. Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu). Consult your doctor if you have been exposed to an infection or for more details.
Tell your health care professional that you are using nilotinib before having any immunizations/vaccinations. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose).
To lower the chance of getting cut, bruised, or injured, use caution with sharp objects like razors and nail cutters, and avoid activities such as contact sports.
Children may be more sensitive to the side effects of this drug, especially liver disease, and slowed growth and development. Consult the doctor or pharmacist for more details. See the doctor regularly so your child's liver function, height, weight, and development can be checked.
Older adults may be more sensitive to the side effects of this drug, especially QT prolongation (see above).
Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while using nilotinib. Nilotinib may harm an unborn baby. Ask about reliable forms of birth control while using this medication and for 14 days after stopping treatment. If you become pregnant, talk to your doctor right away about the risks and benefits of this medication.
It is not known whether this drug passes into breast milk. Because of the possible risk to the infant, breast-feeding while using this drug and for 14 days after stopping treatment is not recommended. Consult your doctor before breast-feeding.
Side Effects of Nilotinib :
Nausea, vomiting, headache, tiredness, constipation, and diarrhea may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
People using this medication may have serious side effects. However, you have been prescribed this drug because your doctor has judged that the benefit to you is greater than the risk of side effects. Careful monitoring by your doctor may decrease your risk.
This medication decreases bone marrow function, an effect that may lead to a low number of blood cells such as red cells, white cells, and platelets. This effect can cause anemia, decrease your body's ability to fight an infection, or cause easy bruising/bleeding. Tell your doctor right away if you develop any of the following serious symptoms: severe tiredness, pale skin, signs of infection (such as sore throat that doesn't go away, fever, chills), easy bruising/bleeding (such as bloody/black stool, bloody/pink urine).
Nilotinib sometimes causes side effects due to the rapid destruction of cancer cells (tumor lysis syndrome). To lower your risk, your doctor may add a medication and tell you to drink plenty of fluids. Tell your doctor right away if you have symptoms such as: low back/side pain (flank pain), signs of kidney problems (such as painful urination, change in the amount of urine), muscle spasms/weakness.
Tell your doctor right away if you have any serious side effects, including: severe stomach/abdominal pain, toe/joint pain, swelling hands/ankles/feet, unusual/rapid weight gain, symptoms of high blood sugar (such as increased thirst/urination), signs of liver disease (such as nausea/vomiting that doesn't stop, stomach/abdominal pain, yellowing eyes/skin, dark urine).
Get medical help right away if you have any very serious side effects, including: fast/pounding/irregular heartbeat, severe dizziness, fainting, seizures, signs of a heart attack (such as chest/jaw/left arm pain, shortness of breath, unusual sweating), signs of a stroke (such as weakness on one side of the body, trouble speaking, sudden vision changes, confusion), signs of bleeding in the brain (such as sudden severe headache, sudden vision changes, confusion, loss of consciousness), signs of blood circulation disease (such as numbness/pain in the legs, leg pain with physical activity, decrease in walking distance).
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Drug Interactions of Nilotinib :
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Some products that may interact with this drug include: antacids, flibanserin, H2 blockers (such as cimetidine/famotidine), proton pump inhibitors (such as omeprazole).
Other medications can affect the removal of nilotinib from your body, which may affect how nilotinib works. Examples include azole antifungals (such as itraconazole, ketoconazole), HIV protease inhibitors (such as ritonavir), macrolide antibiotics (such as clarithromycin), rifamycins (such as rifabutin), St. John's wort, drugs used to treat seizures (such as carbamazepine, phenytoin), among others.
Many drugs besides nilotinib may affect the heart rhythm (QT prolongation), including amiodarone, dofetilide, pimozide, procainamide, quinidine, sotalol, macrolide antibiotics (such as erythromycin), among others.
Missed dose of Nilotinib :
If you miss a dose, take it as soon as you remember, but do not take if it is less than 2 hours before or 1 hour after a meal. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Over dose of Nilotinib :
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call a poison control center right away.
Storage of Nilotinib :
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Other Information of Nilotinib :
FOR BEST RESULTS, this medicine should be used along with exercise, a low-cholesterol/low-fat diet, and a weight loss program if you are overweight. FOLLOW THE DIETARY PLAN provided by your doctor. DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children and pets. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.
Cost Of Nilotinib : The lowest MyGenericPharmacy.com price for the most common version of Tasigna (Nilotinib) is around $21.00, 51% off the average online retailing price of $1204.00.
MISSPELLINGS OF NILOTINIB :
Tasignna, Tasigina, Tasinga, Tasignah, Tasignaax, Tasiggna, Tasignaaz, Tasignea, Tasignna, Tasignaaa, Tasigana, Tasignnaah, Tasignae, Tasiginaa, Tasiginaax,
Tazigna, Tasina, Tasinga, Tasynha, Nilotinibb, Nilotnib, Nilotiniib, Nilotinibx, Nilotinibz, Nilotineb, Nilotinip, Nilotinnib, Nilotiniv, Nilotinob, Nilotanib, Nilotnibb, Nilotonib, Nilotinieb, Nilotinibe, Nilotinibe, Nilotib, Nilotinibbe, Nilothinib,
Nilotenib, Nilotynib.
FAQ
1. What is Nilotinib and what is it used for?
Nilotinib is a medical drug that belongs to a class of medication called Kinase inhibitors. This medicine is used to treat certain types of white blood cell cancer called leukemia as a recently identified disease in adults and children 1 years and older.
2. Is nilotinib a chemotherapy drug?
Approved by U.S. food and drug administration, Nilotinib is an oral chemotherapy drug, manufactured by Novartis. It is prescribed to treat specific types of blood cancer called Philadelphia chromosome-positive chronic myeloid leukemia.
3. What is the difference between imatinib and nilotinib?
As per manufacturer, nilotinib is a more potent and selective BCR-ABL inhibitor than imatinib. However, Nilotinib showed significantly lower progression rate during the first year of treatment when compared with Imatinib.
4. Does Nilotinib cause hair loss?
An individual can expect loss of hair during treatment with Nilotinib. As per reports, 13% of people undergoing nilotinib treatment experience hair loss i.e. higher when compared with Imatinib that showed 7% hair loss.
5. How long do you take nilotinib?
The course of treatment is generally determined by the response of the condition to the medicine. However, an ideal course time of 3 years is monitored. If the condition meets certain criteria, treatment with nilotinib is replaced with another appropriate treatment.
6. What are the side effects of using Nilotinib?
Common side effects if using Nilotinib are Headache, vomiting, nausea, Diarrhea, upper respiratory infections, fever, rash, runny or stuffy nose, vomiting, increased liver enzymes in blood, etc. Inform the doctor if these conditions persist or get worse.
7. What happens if you take Nilotinib with food?
Nilotinib must be taken in an empty stomach as per doctor's prescription. Taking this medicine with food can cause rise of nilotinib levels in the blood in an unpredictable way. This results in nilotinib toxicity which increases the risk of harmful side effects to the body.
8. Can you take ibuprofen with Nilotinib?
According to integrative studies, no interaction was found between ibuprofen and Nilotinib. However, this does not absolutely justify the safety between both drugs. Consult your healthcare professional before medicating with both drugs together.
9. Is nilotinib safe during pregnancy?
According to animal studies, nilotinib might cause fetal deformities as it is found to be contraindicated during pregnancy. However, this concept may not apply to humans. A pregnant woman must use this medicine if its benefits outweigh the potential risk to the unborn child.
