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Generic Afinitor (tm) Everolimus 5mg

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Generic Name : Everolimus
Therapy : Cancer
Per Pill Price : $0.00

Generic Afinitor (tm) Everolimus 5mg

Brand : Afinitor
$450.00 Ships within 24 hours.
Retail price at other pharmacies : $600.00
You Save : 25%
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Buy Generic Afinitor (Everolimus) Online

Buy Most Prescribed Everolimus – Now at 25% Discount.

About Generic Afinitor® (Everolimus)

Key Details

  1. Generic Afinitor™ 5 mg for Cancer
  2. Buy online Generic Afinitor™ 5mg (10 Pills), Afinitor Cost, Price $450.00 at 25% Discount
  3. Targeted therapy for multiple cancers
  4. Overcomes endocrine resistance in breast cancer
  5. Oral once-daily dosing

How Generic Afinitor Works

Generic Afinitor inhibits the mTOR pathway, which is often overactive in cancer cells. By blocking this pathway, it slows tumor growth, reduces blood vessel formation, and induces apoptosis.

In hormone receptor–positive breast cancer, everolimus enhances the effectiveness of endocrine therapy by overcoming resistance. Its targeted action allows cancer control with manageable toxicity.

Drug Info

EVEROLIMUS– ORAL (eh ve RO li mus)
Common Brand Name(s): Afinitor™

Other name brands for this medication
Zortress, Afinitor Disperz, Evermil, Rolimus, Rapact, Volantis, Evertor, Everotas, Evergraf, Boletraaz

Uses of Afinitor

Everolimus is used to treat advanced (late-stage) cancers or noncancerous tumors, such as kidney and breast cancer, subependymal giant cell astrocytoma (SEGA, a brain tumor), renal angiomyolipoma (kidney tumor), and partial-onset seizures (epilepsy) with tuberous sclerosis complex (TSC), and neuroendocrine tumors of the pancreas, stomach or bowels, and lungs. It is used for patients who have already received other medicines that did not work well or those who will not be treated with surgery.

Everolimus works by interfering with the growth of cancer cells, which are eventually destroyed by the body. Since the growth of normal body cells may also be affected, other unwanted effects will also occur. It belongs to the group of medicines known as antineoplastics (cancer medicines).

Everolimus is also used together with other medicines to lower the body's natural immunity in patients who receive kidney or liver transplants. When a patient receives an organ transplant, the body's white blood cells try to get rid of (reject) the transplanted organ. Everolimus works to suppress the immune system and prevents the white blood cells from getting rid of the transplanted organ.

This medicine is available only with your doctor's prescription.

Before Using Afinitor

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.  

How to Use Afinitor

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

If you have a kidney or liver transplant, you might have to take this medicine for the rest of your life to prevent rejection of the organ. Do not change your dose or stop taking this medicine without checking first with your doctor.

This medicine comes with a Medication Guide and patient information leaflet. Read and follow these instructions carefully. Ask your doctor if you have any questions.
Take this medicine the same way every day. Take it at the same time and consistently either with or without food.

Swallow the regular tablet whole with a glass of water. Do not crush, break, or chew it. If you accidentally break or crush the tablet, wash your hands with water right away.

Do not swallow the tablet for suspension. It must be dissolved in water before you take the medicine. If you are preparing the oral suspension for another person, wear disposable gloves.

    To dissolve the tablet for suspension in an oral syringe:
  1. Use a syringe that measures 10 milliliters (mL). Pull out the plunger and put the tablet in the barrel of the syringe. Replace the plunger and push it until it touches the tablet.
  2. Fill a small glass with 30 mL (2 tablespoons) of water. Place the syringe tip in the water and draw up enough water to cover the tablet and to fill half of the syringe. Hold the syringe with the tip up and draw in 4 mL of air. Place the syringe in an empty glass with the tip up and wait 3 minutes.
  3. Slowly turn the syringe up and down 5 times but do not shake it. Hold the syringe with the tip up and push the plunger to remove most of the air. Place the syringe in the mouth and slowly give the dose.
  4. Fill the syringe with 5 mL of water from the small glass. Hold the tip up and add 4 mL of air. Swirl the water in the syringe to rinse any extra medicine from the sides. Hold the syringe with the tip up and push the plunger to remove most of the air.
        Place the syringe in the mouth and slowly give the liquid. Use a new syringe for each dose.

Side Effects of Afinitor

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:
More common

    Bloating or swelling of the face, arms, hands, lower legs, or feet
    bloody nose
    chest pain or tightness
    chills
    cough
    decreased weight
    diarrhea
    difficult or labored breathing
    difficulty with swallowing
    fever
    general feeling of discomfort or illness
    hoarseness
    lower back or side pain
    painful or difficult urination
    rapid weight gain
    sores, ulcers, or white spots on the lips, tongue, or inside the mouth
    tingling of the hands or feet

Precautions

It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Blood and urine tests may be needed to check for unwanted effects.

Using this medicine while you are pregnant can harm your unborn baby. It may also cause birth defects if the father is using it when his sexual partner becomes pregnant. Female patients should use an effective form of birth control during treatment with this medicine and for at least 8 weeks after the last dose. Male patients who have female partners should use effective birth control during treatment with Afinitor®or Afinitor® Disperz and for 4 weeks after the last dose. If you think you have become pregnant while using the medicine, tell your doctor right away.

If you are planning to have children, talk with your doctor before using this medicine. Some men and women using this medicine have become infertile (unable to have children).

This medicine may cause a serious lung problem called interstitial lung disease or non-infectious pneumonitis. Check with your doctor right away if you have chest pain, chills, cough, fever, or trouble breathing.

Check with your doctor right away if you have bloody urine, a decrease in frequency or amount of urine, an increase in blood pressure, increased thirst, loss of appetite, lower back or side pain, nausea, swelling of the face, fingers, or lower legs, troubled breathing, unusual tiredness or weakness, vomiting, or weight gain. These may be symptoms of a serious kidney problem.

While you are being treated with everolimus, and after you stop treatment with it, do not have any immunizations (vaccines) without your doctor's approval. Everolimus may lower your body's resistance and the vaccine may not work as well or you might get the infection the vaccine is meant to prevent. In addition, you should not be around other persons living in your household who receive live virus vaccines because there is a chance they could pass the virus on to you. Some examples of live virus vaccines include measles, mumps, influenza (nasal flu vaccine), poliovirus (oral form), rotavirus, and rubella. Do not get close to them and do not stay in the same room with them for very long. If you have questions about this, talk to your doctor.

Everolimus can temporarily lower the number of white blood cells in your blood, which increases the chance of getting an infection. It can also lower the number of platelets, which are necessary for proper blood clotting. If this occurs, there are certain precautions you can take, especially when your blood count is low, to reduce the risk of infection or bleeding:

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

    Ritonavir

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

    Adenovirus Vaccine Type 4, Live
    Adenovirus Vaccine Type 7, Live
    Bacillus of Calmette and Guerin Vaccine, Live
    Benazepril
    Boceprevir
    Captopril
    Carbamazepine
    Ceritinib
    Cholera Vaccine, Live
    Clarithromycin
    Cobicistat
    Conivaptan
    Curcumin
    Dengue Tetravalent Vaccine, Live
    Dronedarone
    Duvelisib
    Enalapril
    Enalaprilat
    Enzalutamide
    Fosinopril
    Fosnetupitant
    Fosphenytoin
    Idelalisib
    Indinavir
    Influenza Virus Vaccine, Live
    Itraconazole
    Ivosidenib
    Ketoconazole
    Larotrectinib
    Lisinopril
    Lopinavir
    Lorlatinib
    Lumacaftor
    Measles Virus Vaccine, Live
    Mitotane
    Moexipril
    Mumps Virus Vaccine, Live
    Nefazodone
    Nelfinavir
    Netupitant
    Perindopril
    Phenytoin
    Poliovirus Vaccine, Live
    Posaconazole
    Quinapril
    Ramipril
    Ribociclib
    Rifampin
    Rotavirus Vaccine, Live
    Rubella Virus Vaccine, Live
    Saquinavir
    Smallpox Vaccine
    St John's Wort
    Telaprevir
    Telithromycin
    Tofacitinib
    Trandolapril
    Typhoid Vaccine
    Varicella Virus Vaccine, Live
    Venetoclax
    Verapamil
    Voriconazole
    Yellow Fever Vaccine
    Zofenopril
    Zoster Vaccine, Live

Missed Dose

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Overdose

If overdose is suspected, contact a poison control center or emergency room immediately.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Cost of Afinitor

The lowest MyGenericPharmacy.com price for the most common version of Afinitor (Everolimus) is around $45.00, 25% off the average online retailing price of $600.00.

What is Afinitor / Everolimus?
Afinitor is an oral targeted anticancer and immunosuppressive medication used to treat various cancers, including advanced breast cancer, renal cell carcinoma, neuroendocrine tumors, and subependymal giant cell astrocytoma (SEGA). It is also used in certain tuberous sclerosis–associated conditions.

How Does Afinitor Work?
Everolimus is an mTOR (mammalian target of rapamycin) inhibitor that blocks intracellular signaling involved in cell growth, proliferation, and angiogenesis. This leads to reduced tumor cell growth and survival.

Benefits of Afinitor
  1. Targeted therapy for multiple cancers
  2. Overcomes endocrine resistance in breast cancer
  3. Oral once-daily dosing
  4. Inhibits tumor growth and angiogenesis
  5. Useful in rare tumor syndromes (TSC)

Dosage & How to Use
  1. Taken orally once daily
  2. Typical dose: 10 mg once daily
  3. Can be taken with or without food (consistently)
  4. Swallow tablets whole
  5. Continue until disease progression or unacceptable toxicity

Side Effects & Precautions
Common side effects may include:
  1. Stomatitis (mouth ulcers)
  2. Rash
  3. Fatigue
  4. Diarrhea
  5. Infections
Precautions:
  1. Monitor blood counts regularly
  2. Monitor renal function and glucose levels
  3. Avoid live vaccines
  4. Use prophylactic mouthwash to reduce stomatitis

Who Should Not Take Afinitor
  1. Hypersensitivity to everolimus or rapamycin derivatives
  2. Pregnancy and breastfeeding
  3. Severe hepatic impairment (dose adjustment required)
  4. Active uncontrolled infections


Other Information of Afinitor :
FOR BEST RESULTS, this medicine should be used along with exercise, a low-cholesterol/low-fat diet, and a weight loss program if you are overweight. FOLLOW THE DIETARY PLAN provided by your doctor. DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children and pets. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.

MISSPELLINGS OF AFINITOR :
Afinitorr, Afinitor, Afinitorx, Afinitior, Afinitorr, Afinotir, Afinator, Afintior, Afinotorr, Afinitorrx, Affinitor, Afinittor, Afinatorr, Afinitore, Afinotirx, Afinitar, Affinator, 
Afenitor, Affinitore, Afynitor, Afinniitor, Everolimusx, Everolimusz, Everolamious, Everolimusm, Everolimos, Evorolimus, Everolimuss, Everolimius, Evorolimus, Everolimusv, Everolimusne, Everolmius, Everolimusl, Everolimuss, Everolimosx, 
Everolymus, Everollimus, Everolimous, Evrolimus, Everolemus, Everolimos, 
Everolymos, Everalimus, Evorolimus.

FAQ

1. What is Everolimus (Afinitor) and what is it used for?
Everolimus is a medical drug sold under the brand name Afinitor which belongs to a class of medication called kinase inhibitors. This medicine is used as an immune system suppressant to prevent the ability of rejection from the immune system for transplanting organs and in treatment of several cancers and tumors.

2. When and how to use Everolimus?
Everolimus is available to us as a form of pill that must be taken by mouth usually without food on an empty stomach or as per your doctor's prescription. It is usually taken once every 12 hour. The dosage is based on your medical condition, treatment response, laboratory test and other corresponding treatment that you may be taking. Avoid taking medications that lowers the stomach acid as the effectiveness of Erlotinib may get reduced. Take this medicine at the same time daily to get the most benefits from it. Do not increase the dosage or take it more often than prescribed as the risk of side effects may get increased without any improvement to the symptoms. Discuss all the simultaneous medication that you may be taking with Erlotinib. Follow the medical guide carefully and inform your doctor in case of any confusion.

3. What are the side effects of Everolimus?
Common side effects observed while medicating with Everolimus are nausea, constipation, headache, Sore in mouth or throat may occur. Inform your doctor if these conditions persist or get worse. There are some serious side effects which must be informed to the doctor right away if observed like wound problems (such as infection, slow wound healing, opening of wound), decreased sexual ability (in men), chest pain/pressure, shortness of breath, unusual bruising/bleeding, swelling hands/ankles/feet etc. There are also some allergic and severe side effects which must get immediate medical attention if observed like clumsiness, loss of coordination, weakness, sudden change in your thinking (such as confusion, difficulty concentrating), difficulty moving your muscles, problems with speech, seizures, vision changes, severe dizziness, fainting, severe dizziness, trouble breathing, rash, itching/swelling etc. You need to check sugar and cholesterol periodically as this medicine may have affect on them. It may also affect male and female fertility.

4. How effective is Everolimus?
Everolimus is an effective treatment for advanced and metastatic cancer of breast in the positive case of hormone receptors. In a clinical test, people dealing with kidney cancer have a response rate of 2% from everolimus. It may be prescribed medicine for kidney cancer in adults who couldn't find positive results in a few other medications.

5. How long does it take for everolimus to work?
Everolimus is a medicine used in treating several cancers and tumors. However, this medicine is meant to be taken as a long term medication. According to a clinical trial, everolimus for a duration of 24 months.

6. How long can you take Everolimus?
Everolimus is usually taken every day for so long as it is running or until unacceptable side consequences arise. It is supposed to be taken as a long-time period remedy. In medical trials, the average period of treatment turned into about 24.0 weeks (variety one week to almost 200 weeks).

7. Can you drink on everolimus?
Do no longer drink or consume meals for at least 1 hour after swishing and spitting the mouthwash. You need to not eat grapefruit or drink grapefruit juice while you take this remedy. Grapefruit and grapefruit juice might also motive better degrees of everolimus in the frame. This can bring about more unwanted consequences.

8. Does everolimus cause memory problems?
Everolimus had damaging results on depressive and tension-like behavior in mice. Everolimus, growing neurogenesis, had wonderful results on memory overall performance. mTOR inhibitors may improve cognitive function or guard from cognitive decline.


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