Buy Generic Eldepryl (Selegiline) Online

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About Generic Eldepryl® (Selegiline)

Key Details

1. Generic Eldepryl™ 5 mg for Parkinsons Disease
2. Buy online Generic Eldepryl™ 5 mg (60 Pills), Eldepryl Cost, Price $13.80 at 85% Discount
3. Improves Parkinson’s symptoms
4. Increases dopamine availability
5. Reduces “off” time with levodopa

How Generic Eldepryl Works

After oral administration, selegiline selectively inhibits the MAO-B enzyme in the brain. This enzyme is responsible for the breakdown of dopamine.

By reducing dopamine degradation, selegiline increases dopamine levels in the basal ganglia. This enhances dopaminergic activity and improves motor symptoms such as tremor, rigidity, and bradykinesia.

Drug Info

SELEGILINE – ORAL (se LE ji leen)
Common Brand Name(s): Eldepryl™

Other name brands for this medication
Emsam, Zelapar, Jumex, Carbex, Selgin, Elegelin, Jumax, Selgelin, Selerin

Uses of Eldepryl

This medication is used to treat movement disorders caused by Parkinson's disease. It does not cure Parkinson's disease, but it may improve shakiness (tremor), muscle stiffness, loss of normal movement as your dose of other Parkinson's medication wears off (end-of-dose failure), and sudden switching between normal movement and stiffness ("on-off" problems). It may improve your range of motion and ability to walk, dress, and exercise. Selegiline is usually used in combination with other medicines (e.g., levodopa, carbidopa).
Selegiline is an enzyme blocker (MAO inhibitor) that works by slowing the breakdown of certain natural substances in the brain (neurotransmitters such as dopamine, norepinephrine, and serotonin).

Before Using Eldepryl

Before taking selegiline, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

How to Use Eldepryl

Take this medication by mouth, usually twice daily with breakfast and lunch. Taking selegiline late in the day may cause trouble sleeping. Dosage is based on your medical condition and response to therapy. Do not increase your dose or take it more often than directed.
After you have been taking selegiline for 2 or 3 days, your doctor may direct you to lower your levodopa dose. Follow your doctor's instructions closely. Do not stop or change the dose of any of your medications without first talking with your doctor.
It may take a few weeks for the full benefits of the drug to be noticed. Do not stop taking this drug without first consulting your doctor. Talk with your doctor if the medication stops working well or if your condition worsens.

Side Effects of Eldepryl

Dizziness, abdominal pain, dry mouth, nausea, stomach upset, trouble sleeping, and headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. If you are also taking levodopa, you may experience more side effects from the levodopa when taking selegiline. Tell your doctor immediately if any of these side effects occur: nausea, shakiness, muscle stiffness, mental/mood changes such as hallucinations/abnormal dreams. Your doctor may need to change your medication or dose. Do not stop or change the dose of your levodopa without talking with your doctor first.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Some people taking selegiline have fallen asleep suddenly during their usual daily activities (such as talking on the phone, driving). In some cases, sleep occurred without any feelings of drowsiness beforehand. This sleep effect may occur anytime during treatment with selegiline, including up to 1 year after starting the medication. If you experience increased sleepiness or fall asleep during the day, do not drive or take part in other possibly dangerous activities until you have discussed this effect with your doctor. Your risk of this sleep effect is increased by using alcohol or other medications that can make you drowsy. See also Precautions section.
Tell your doctor right away if you have any serious side effects, including: fainting, loss of balance, mental/mood changes (e.g., agitation, confusion, depression, hallucinations), unusual strong urges (such as increased gambling, increased sexual urges), worsening muscle stiffness/twitching, changes in sexual ability/interest, increased shaking (tremor), swollen ankles/legs, difficulty urinating, unusual weight gain, easy bleeding/bruising, black/tarry stools, vomit that looks like coffee grounds.
This drug may rarely cause an attack of extremely high blood pressure (hypertensive crisis), which may be fatal. Many drug and food interactions can increase this risk. (See also Drug Interactions section.) Get medical help right away if any of these serious side effects occur: frequent/severe headache, fast/slow/irregular/pounding heartbeat, chest pain, neck stiffness/soreness, severe nausea/vomiting, sweating/clammy skin (sometimes with fever), widened pupils, vision changes (e.g., double/blurred vision), sudden sensitivity to light (photophobia).
This medication may increase serotonin and rarely cause a very serious condition called serotonin syndrome. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take. Get medical help right away if you develop some of the following symptoms: hallucinations, unusual restlessness, loss of coordination, fast heartbeat, severe dizziness, unexplained fever, severe nausea/vomiting/diarrhea, twitching muscle.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

Before using this medication, tell your doctor or pharmacist your medical history, especially of: a certain kind of adrenal gland tumor (pheochromocytoma), cerebrovascular disease (e.g., stroke), heart problems (e.g., congestive heart failure, heart attack), bleeding problems, history of severe/frequent headaches, peptic ulcer, diabetes, personal/family history of mental/mood disorders (e.g., schizophrenia, bipolar disorder), personal/family history of high blood pressure, liver disease, overactive thyroid (hyperthyroidism).
This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages. See also Side Effects section. To minimize dizziness and the risk of fainting, get up slowly when rising from a sitting or lying position.
Before having surgery, tell your doctor or dentist you are taking this medication. You may need to stop taking this drug beforehand. Follow your doctor's instructions carefully. Selegiline should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known if this drug passes into breast milk. Consult your doctor before breast-feeding.

Drug Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Some products that may interact with selegiline include: antidepressants (including bupropion, maprotiline, mirtazapine), other MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, tranylcypromine), appetite suppressants (such as diethylpropion), drugs for attention deficit disorder (such as atomoxetine, methylphenidate), apraclonidine, buspirone, carbamazepine/oxcarbazepine, cyclobenzaprine, certain herbal products (such as ephedra/ma huang), cold medications/nasal decongestants (such as phenylephrine, phenylpropanolamine, pseudoephedrine), fentanyl, street drugs (such as LSD, mescaline), stimulants (such as amphetamines, ephedrine), supplements (such as tryptophan, tyramine), tetrabenazine, certain "triptans" used to treat migraine headaches (such as rizatriptan, sumatriptan, zolmitriptan).
The risk of serotonin syndrome/toxicity increases if you are also taking other drugs that increase serotonin. Examples include street drugs such as MDMA/"ecstasy," St. John's wort, dextromethorphan, certain antidepressants (including SSRIs such as fluoxetine/paroxetine, SNRIs such as duloxetine/venlafaxine, TCAs such as amitriptyline/doxepin), certain narcotic medications (such as meperidine, methadone, pentazocine, propoxyphene, tramadol, tapentadol), among others. The risk of serotonin syndrome/toxicity may be more likely when you start or increase the dose of these drugs.
Tell your doctor or pharmacist if you are using any of these medications before, during, or within 2 weeks after treatment with selegiline. Tell your doctor or pharmacist if you have taken fluoxetine during at least 5 weeks before starting selegiline. Discuss with your doctor how much time to wait between starting or stopping any of these drugs and taking selegiline.
Check the labels on all your medicines (such as allergy, cough-and-cold products, diet pills) because they may contain dextromethorphan, decongestants, or stimulants. Ask your pharmacist about the safe use of those products.
To prevent a very serious high blood pressure reaction, it is very important that you follow a special diet recommended by your doctor or dietician in order to limit your intake of tyramine while you are taking this medicine. Avoid foods and beverages that are high in tyramine, including: aged cheeses (e.g., bleu, cheddar, parmesan), dried/aged/fermented meats and sausages (e.g., salami, liverwurst), preserved fish (e.g., pickled herring), products containing large amounts of yeast (e.g., concentrated yeast extract, bouillon cubes, powdered soup/gravy, homemade or sourdough bread), fermented foods (e.g., sauerkraut, kim chee), most soybean products (e.g., soy sauce, tofu), broad/fava beans, red wine, sherry, tap beers, vermouth. Limit or avoid foods that are moderate in tyramine, including: avocados, bananas, eggplant, green beans, raisins, raspberries, red plums, spinach, tomatoes, chocolate, cultured dairy products (e.g., buttermilk, yogurt, sour cream), fish eggs, pate, peanuts, coffee, cola, alcohol-free beer, bottled beer, distilled spirits, port, white wine. Consult your doctor or dietician for more details and a complete list of other tyramine-containing foods you should limit or avoid. Seek immediate medical attention if you notice symptoms of very high blood pressure such as unusually fast/slow heartbeat, vomiting, unexplained sweating, headache, chest pain, sudden vision changes, weakness on one side of the body, slurred speech.
This medication may interfere with certain medical/laboratory tests (including brain scan for Parkinson's disease), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Overdose

If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include nausea, vomiting, fast or irregular heartbeat, unusual drowsiness or dizziness, and loss of consciousness.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Cost of Eldepryl

The lowest MyGenericPharmacy.com price for the most common version of Eldepryl (Selegiline) is around $0.23, 85% off the average online retailing price of $93.00.

What is Eldepryl / Selegiline?
Eldepryl is a medication containing selegiline, used in the treatment of Parkinson’s disease. It helps improve motor symptoms by increasing dopamine levels in the brain.

How Does Eldepryl Work?
Selegiline is a selective monoamine oxidase-B (MAO-B) inhibitor. It prevents the breakdown of dopamine, increasing its availability in the brain.

Benefits of Eldepryl

1. Improves Parkinson’s symptoms
2. Increases dopamine availability
3. Reduces “off” time with levodopa
4. May delay need for levodopa (early disease)
5. Oral convenient dosing

Dosage & How to Use

1. Taken orally as tablets or orally disintegrating tablets
2. Usual dose: 5 mg twice daily (morning and noon)
3. Avoid taking in the evening (may cause insomnia)
4. Used alone or with levodopa
5. Dose adjusted based on response

Side Effects & Precautions
Common side effects may include:

1. Insomnia
2. Nausea
3. Dizziness
4. Dry mouth
5. Headache

Precautions:

1. Avoid taking late in the day (insomnia)
2. Avoid combining with SSRIs/SNRIs/TCAs without supervision
3. Limit high-tyramine foods
4. Monitor for hallucinations
5. Use caution in elderly

Who Should Not Take Eldepryl

1. Patients taking other MAO inhibitors
2. Individuals on certain antidepressants (without supervision)
3. Patients with hypersensitivity to selegiline

Other Information of Eldepryl :
DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.

MISSPELLINGS OF ELDEPRYL :
Eldepryl, Eldepryl, Eldpryl, Elldepryl, Eldepril, Eldepryll, Eldepry, Eldepral, Eldeprylx, Eldepryel, Eldepyril, Eldperyl, Eldapryl, Eldepril, Eldapril, Eldeperyl, 
Elldepryl, Eldepril, Eldipryl, Selegiline, Selejiline, Selgiline, Selegeline, Selejiline, Selejiline, Selegilline, Sellegiline, Selegilin, Selegilene, Selegilne, Selejilene, 
Selejiline, Selligiline, Cellegine, Selijillin.

FAQ

1. What is Selegiline (Selgin) and what is it used for?
Selegiline is a medical drug available to us under the brand name Selgin is a medicinal drug used for the treatment of nervous disorder called Parkinson's disease. This medicine belongs to a class of medication called MAO inhibitors. It works by increasing a natural substance inside the brain which controls the movement of your body.

2. When to use Selegiline?
Selegiline is available to us in a form of capsules or tablets that must be taken usually twice a day. Generally take this medicine at breakfast and lunch. Follow the prescription label of the following doctor carefully. This medicine will help you to control the symptoms of Parkinson's and not cure them. Better to take this medicine twice at the same time. Swallow the tablet whole rather than chewing or crushing it in your mouth. Do not increase your dosage or take it more often than prescribed. In case of any confusion or irregularity, inform the doctor accordingly.

3. What are side effects of Selegiline?
Side effects of Selegiline which must be informed to the doctor if get worse such as heartburn, fainting, dizziness, vomiting, gas, constipation, sleepiness, nausea, difficulty swallowing, diarrhea, depression, unusual dreams, rash, stomach pain, purple blotches on the skin, lightheadedness etc. Side effects like uncontrollable shaking of a part of your body, sweating, chest pain, hallucinations , stiff or sore neck, difficulty breathing, unusual movements that are difficult to control, irregular, or pounding heartbeat must be informed to the doctor immediately.

4. How effective is Selegiline?
Selegiline is considered as an effective and reliable medication in treatment of severe depression. Selegiline increases dopamine(Substance that is present in the brain to control movements) in the nervous system. Don't stop taking this medicine suddenly or it may have some serious side effects on your body. Always consult your doctor in case of withdrawal or resuming of dosage.

5. How quickly does Selegiline works?
Selegiline is a kind of medicine that is started from a low dose and than increased gradually. It may take few weeks to reach the best dose for your. The effects can be seen anywhere between 4-12 weeks of daily medication

6. What precautions must be taken before medicating with Selegiline?
Before starting the medication with Selegiline, one must inform the doctor regarding allergies related to it, or any other allergies as these products may contain some ingredient that causes an allergic reaction inside your body. Inform your doctor if you have a medical history related to diabetes, cerebrovascular diseases, heart disease, high cholesterol, frequent headache, peptic ulcers, kidney disease, sleep disorders, hypotension, bleeding problems, mental/mood disorders, liver disease, etc. Use of alcohol and marijuana while medicating with Selegiline may make you more dizzy than usual which must be avoided especially while handling machinery or doing any physical task.

7. Does Selegiline help with anxiety?
According to the result of studies performed on mice, Selegiline indicates antidepressants and small anxiolytic effects. The study also suggested that Selegiline is an effective medicine for Parkinson's disease for the symptoms such as anxiety and depression as well.

8. Does Selegiline raise blood pressure?
The combination of Selegiline and tyramine could cause an excessive rise in blood pressure which could be dangerous enough to deliver life-threatening side effects. A user must be very clear with the food product that must not be consumed while medicating with Selegiline as the medicine could also cause disabled thinking or response.

9. Can a pregnant woman use Selegiline?
Selegiline is a kind of medicine that must only be used when needed during pregnancy. One must consult with their health professional before medicating with Selegiline. Also, it is not known whether the medicine gets passed on to breast milk or not. Consult your doctor before breastfeeding the baby.

10. Does Selegiline cause weight gain?
An older formulation of Selegiline called phenelzine was most like to cause weight gain in the user's body. However, the result of a newer formulation i.e. Selegiline is associated with weight loss during its medication.

11. Can Selegiline affect Serotonin level?
Selegiline when used together with several other MAO inhibitors such as rasagiline, phenelzine, etc, and several antidepressant medicines such as fluvoxamine, paroxetine, doxepin, etc, could cause a condition called serotonin syndrome.

12. Does Selegiline lower blood pressure?
According to the reports, orthostatic tests and withdrawal from Selegiline decrease the systolic blood pressure remarkably during on-stage supine position. the initial drop of blood pressure in Selegiline withdrawal is significantly higher than that of the orthostatic test. However, no effect on heart rate was observed.