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Generic Ikorel (tm) Nicorandil 5, 10mg

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Generic Name : Nicorandil
Therapy : Vasodilator
Per Pill Price : $0.00

Generic Ikorel (tm) Nicorandil 5, 10mg

Brand : Zynicor
$22.50 Ships within 24 hours.
Retail price at other pharmacies : $55.50
You Save : 59.46%
Strength-Dosage:
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Buy Generic Ikorel (Nicorandil) Online

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About Generic Ikorel® (Nicorandil)

Key Details

  1. Generic Ikorel™ 5 mg for Heart Disease
  2. Buy online Generic Ikorel™ 5mg (30 Pills), Ikorel Cost, Price $22.50 at 59% Discount
  3. Prevents angina attacks
  4. Improves coronary blood flow
  5. Reduces cardiac workload

How Generic Ikorel Works

Generic Ikorel relaxes blood vessels by opening ATP-sensitive potassium channels, leading to arterial dilation and reduced resistance to blood flow. This lowers cardiac workload and helps prevent anginal attacks.

It also has nitrate-like effects that cause venous dilation, reducing preload and myocardial oxygen demand. Together, these actions improve coronary perfusion and relieve ischemic chest pain.

Drug Info

NICORANDIL – ORAL (ny-KOR-an-dil)
Common Brand Name(s): Ikorel™

Other name brands for this medication
Nikoran, Korandil, K-Cor, Nicoduce, K-Ion, Zynicor, Nucoril, Nikos, Nicorex, Mayonil

Uses of Ikorel

Nicorandil is used to prevent and treat chronic angina pectoris. It is a type of drug called a potassium channel activator with a nitrate component. It is used to maintain blood flow to the heart and prevent angina pain. In general this drug is used to increase blood flow through the blood vessels of the heart which prevents angina pectoris.

Benefits of being on this drug can include prevention and/or reduction of complications that may arise from having angina pectoris. Studies have shown that the drug can reduce the risk of having a heart attack (myocardial infarction) and other complications such as coronary artery bypass graft for people with angina pectoris.

Before Using Ikorel

Before taking nicorandil, tell your doctor or pharmacist if you are allergic to it; or to other potassium channel activators; or if you have any other allergies.

How to Use Ikorel

Take this medication orally usually twice daily, with or without food. Use this medication regularly in order to get the most benefit from it. Remember to use it at the same time each day - unless specifically told otherwise by your doctor. Nicorandil has a rapid onset of action. Certain medical conditions may require different dosage instructions as directed by your doctor.

Side Effects of Ikorel

Headaches (especially when medication is first taken)
Nausea and vomiting
Weakness
Dizziness
Flushing of the skin
Muscle pain
Mouth ulcers
Increased or fast heart rate
Abdominal pain
Rectal ulcers and rectal bleeding
Skin and mucosal ulcers
Genital ulcers
Ulcers around stoma
Low blood pressure (hypotension)
If any of these persist or you consider them severe then inform doctor or pharmacist as soon as possible.
Tell your doctor or go to hospital immediately if you develop any of the following symptoms:
Blood in stools or vomit
Yellowing eyes and skin
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have:

Low blood pressure
Cardiogenic shock
A damaged heart which has a low filling pressure
Heart failure
Erectile dysfunction (impotence) and are taking medicines for it such as sildenafil, tadalafil and vardenafil
Before using this medication, tell your doctor or pharmacist your medical history, especially any of the following:
Cardiac problems.
Before having surgery, tell your doctor or dentist that you are taking this medication.
Pregnancy and breastfeeding - please ensure you read the detailed information below

PREGNANCY
The safety of nicorandil has not been established during pregnancy. Therefore nicorandil is not safe to take if you are, or are planning to become, pregnant. Ask your doctor or pharmacist if you have any doubts or questions about this.
It is sensible to limit use of medication during pregnancy whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation. If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

BREAST FEEDING
It is not known whether nicorandil passes into breast milk. The manufacturer therefore states that it should not be taken if you are breastfeeding.
It is sensible to limit use of medication during breastfeeding whenever possible. However, your doctor may decide that the benefits outweigh the risks in individual circumstances and after a careful assessment of your specific health situation. If you have any doubts or concerns you are advised to discuss the medicine with your doctor or pharmacist.

Drug Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.
This drug should not be used with the following medications because very serious, possibly fatal interactions may occur:
Medication for impotence which are phosphodiesterase 5 inhibitors (e.g. sildenafil, tadalafil, vardenafil).
If you are currently using any of these medications, tell your doctor or pharmacist before starting nicorandil.
Before using this medication, tell your doctor or pharmacist of all prescription and non-prescription/herbal products you may use, especially of:
Medication for high blood pressure (antihypertensive drugs)
Medication to widen blood vessels (vasodilators)
Medication for depression
Medication for inflammation (corticosteroids)
This information does not contain all possible interactions. Therefore, before using nicorandil, tell your doctor or pharmacist of all the products you use.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Overdose

If overdose is suspected, contact a poison control center or emergency room immediately.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Cost of Ikorel

The lowest MyGenericPharmacy.com price for the most common version of Ikorel (Nicorandil) is around $0.75, 59% off the average online retailing price of $55.50.

What is Ikorel / Nicorandil?
Ikorel is an anti-anginal medication used for the prevention and long-term treatment of chronic stable angina pectoris. It improves blood flow to the heart and reduces chest pain when other therapies are insufficient or not tolerated.

How Does Ikorel Work?
Nicorandil acts as both a potassium-channel opener and a nitrate-like vasodilator. It dilates coronary arteries and veins, reducing preload and afterload and improving myocardial oxygen supply.

Benefits of Ikorel
  1. Prevents angina attacks
  2. Improves coronary blood flow
  3. Reduces cardiac workload
  4. Useful when beta-blockers or calcium channel blockers are inadequate
  5. Improves exercise tolerance

Dosage & How to Use
  1. Taken orally, usually twice daily
  2. Typical starting dose: 10 mg twice daily
  3. Low start (if headache): 5 mg twice daily
  4. Maintenance dose: 10–20 mg twice daily
  5. Can be taken with or without food
  6. Dose adjusted gradually based on tolerance

Side Effects & Precautions
Common side effects may include:
  1. Headache (very common)
  2. Dizziness
  3. Flushing
  4. Nausea
  5. Hypotension
Precautions:
  1. Monitor blood pressure regularly
  2. Avoid sudden position changes
  3. Use caution with other antihypertensives
  4. Discontinue if ulcers develop

Who Should Not Take Ikorel
  1. Hypersensitivity to nicorandil
  2. Severe hypotension or shock
  3. Acute heart failure with low filling pressure
  4. Concomitant use with PDE-5 inhibitors (e.g., sildenafil, tadalafil)
  5. Use with riociguat


Other Information of Ikorel : 
DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.

MISSPELLINGS OF IKOREL :
Ikoral, Ikorell, Icorel, Ikorel, Ikorrel, Ikorel, Ikoreal, Ikoreel, Ikorel, Ikorle, Icorel, 
Ikerel, Ikerol, Icorell, Ikorrel, Ikorell, Nicorandil, Nicorandill, Nicrandil, Nicoradil, Nicorendel, Nicorandil, Nicorndil, Nikorandil, Nicorandill, Nikorandel, Nicorandell, 
Nicorandell, Nikorandel, Nicorandell.

FAQ

1. What is Nicorandil (Zynicor) and what is it used for?
Nicorandil is a medical drug available to us under the brand name Zynicor which belongs to a class of medication called Nitrate. This medicine is used to treat or prevent chest pain which is generally caused by decreased flow of blood to the heart also called Angina which can be caused by diseases such as coronary artery disease, atherosclerosis and aortic stenosis.

2. What are the side effects of Nicorandil?
Common side effects observed while medicating with Nicorandil are weakness, tiredness, sickness, dizziness, nausea, flushing etc. Inform your doctor if these conditions persist or get worse. There are also some rare but serious allergic reactions to this medicine which requires immediate medical attention if observed such as severe dizziness, trouble breathing, rash, itching/swelling etc.

3. How effective is Nicorandil?
Nicorandil has proven to be an effective medicine with a normal dosage of 10-30 mg in chronic angina. This is assessed objectively with respect to the increase in exercise duration and also the time of segment depression during treadmill exercise.

4. How long does Nicorandil take to work?
Nicorandil is an effective medicine for angina which starts working 1 hour after the dose. However to experience its full effect, Nicorandil may take 4-5 days of regular medication. Nicorandil is a long term medication which even lasts for the rest of the life time in some cases.

5. Does Nicorandil affect your blood pressure or weight?
Nicorandil is a kind of medicine that may affect your blood pressure by lowering the rate. Also people consuming alcohol with this medicine have experienced further decrease in their blood pressure. Also chronic administration of Nicorandil causes remarkable reduction in weight of body according to a study group.

6. Can nicorandil make you breathless?
In case you are allergic to nicorandil, nicotinic acid, nicotinamide or any if the components listed on the end of this leaflet. A few signs of an hypersensitive reaction include pores and skin rash, itching, shortness of breath or swelling of the face, lips or tongue, which may additionally motive difficulty in swallowing or breathing.

7. Is nicorandil safe?
Nicorandil can purpose extreme skin, mucosal, and eye ulceration, including gastrointestinal ulcers, which may progress to perforation, haemorrhage, fistula, or abscess. Stop nicorandil treatment if ulceration occurs — keep in mind the want for opportunity remedy or expert recommendation if angina signs and symptoms worsen.

8. Can you take aspirin with nicorandil?
Speak for your physician before taking drug treatments for inflammation (corticosteroids) or non-steroidal anti-inflammatory drugs such as aspirin, with Nicorandil capsules. If taken together, you'll be more likely to get ulcers or the opposite issues cited above.

9. Can nicorandil cause diarrhea?
It is essential that clinicians are privy to the link among pharmacotherapy, specifically nicorandil and gastrointestinal ulceration and infection inflicting excessive diarrhoea. Drug cessation is the most effective important and right now effective treatment.


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