Generic Jadenu® : Deferasirox
Deferasirox is the chemical name of the active ingredient in Jadenu®
Generic Buy Jadenu™ 500 mg for Iron overload
Buy online Generic Jadenu (tm) 500 mg (30 Pills), Jadenu Cost, Price $79.50 at 49% Discount.
Other name brands for this medication
Exjade, Jadenu Sprinkle, Defrijet, Desirox, Asunra, Oleptiss, Deferataj, Deferglob, Ferasiro, Thalep
Possible Uses of Deferasirox :
This drug is used to treat persistently high iron levels in the body brought on by repeated blood transfusions. Additionally, it is used to treat non-transfusion-dependent thalassemia, a blood condition in which individuals have high iron levels but do not require blood transfusions. By attaching to iron, it causes the body to excrete excess iron in the stool. Deferasirox is a member of the group of medications known as iron-chelating agents.In some blood illnesses (such sickle cell disease and anaemia), frequent blood transfusions are frequently required. Blood transfusions have a lot of positive effects, but they can also make the body retain too much iron. The additional iron can accumulate in the body and lead to issues including diabetes, liver disease, and heart failure. The chance of developing these disorders can be reduced by getting rid of superfluous iron.
Before using Deferasirox :
Before taking deferasirox, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
How to take Deferasirox :
Before beginning to take deferasirox and each time you obtain a refill, read the medication guide that your chemist has provided. Ask your physician or chemist if you have any questions.
As prescribed by your doctor, often once daily, take this medication by mouth on an empty stomach or with a light meal (such as a whole-wheat english muffin with jelly and nonfat milk). Avoid taking this medication with a meal that has a lot of calories and fat (more than 250 calories), since it could make you more susceptible to side effects. For more information, speak to your doctor or chemist.
With water or other liquids, take the pills. If the tablets are difficult for you to swallow, you can smash them and mix them with soft foods (such yoghurt or applesauce). As soon as possible, swallow the entire drug/food combo. Don't make a supply ahead of time.
If you're using sprinkle granules, sprinkle the recommended dosage on soft food (such applesauce or yoghurt) and consume it all at once.
Deferasirox may bind to aluminum-containing antacids, which may change how effective deferasirox is. Do not combine this medication with aluminum-containing antacids.
To reap the greatest benefits from this drug, take it frequently. Take it at the same time every day to aid in memory. usage this medication just as directed and never up the dosage, frequency, or duration of usage. Your condition won't get better any faster, and your chance of experiencing negative effects will rise.
The dosage is determined by your medical history, weight, laboratory results, and treatment response. If you have specific side effects, your dosage may need to be reduced or your therapy may need to be stopped. Carefully adhere to your doctor's directions.
Precautions When Using Deferasirox :
If you have a medical history of renal illness, liver disease, low platelet counts, advanced cancer, or certain bone marrow problems involving damaged blood-forming cells (high-risk myelodysplastic syndromes), be sure to let your doctor or chemist know before taking this drug.
You can feel lightheaded or have blurry vision if you take this medication. You may feel more lightheaded after consuming alcohol or cannabis. Until you can do something safely, avoid using machinery, driving, or doing anything else that requires attentiveness or sharp vision. Limit your alcohol consumption. If you use marijuana (cannabis), speak with your doctor.
Inform your surgeon or dentist about all the products you use, including prescription, over-the-counter, and herbal medications.
If you experience any illness (such as a fever, diarrhoea, or vomiting) that could lead to dehydration or if you are unable to consume fluids, call your doctor straight once. Particularly in children, the doctor may need to discontinue or modify the deferasirox regimen.
Children may be more vulnerable to this medication's negative effects, including renal issues and hearing loss.
The adverse effects of this medication, particularly liver issues, stomach/intestinal bleeding, and ulcers, may be more severe in older persons.
If you are pregnant or want to become pregnant, let your doctor know. Deferasirox use should not be used with pregnancy. Deferasirox might be harmful to an unborn child. Consult your doctor as soon as possible about the dangers and advantages of this drug if you find out you're pregnant.
It is unknown if this medication passes into breast milk. Because of the possible risk to the infant, breast-feeding while using this medication is not recommended. Consult your doctor before breast-feeding.
Side Effects of Deferasirox :
There could be nausea, vomiting, diarrhoea, or lightheadedness. Inform your doctor or chemist as soon as possible if any of these side effects persist or get worse.
Keep in mind that your doctor has recommended this medication because they believe it will benefit you more than it will harm you. Many users of this medicine report no significant negative effects.
If you experience any severe adverse effects, such as hearing loss or vision abnormalities (such as impaired vision), call your doctor straight away.
Due to the medication's decreased bone marrow function, there may be fewer red, white, and platelet blood cells in the body. This effect may make anaemia worse, reduce your body's capacity to fight an infection, or make you more prone to bleeding and bruising. If you experience any of the following unlikely symptoms, contact your doctor straight away: Unusual fatigue, pale skin, infection-related symptoms (such as a persistent sore throat, fever, and chills), and easy bruising and bleeding.
Rarely, this medication may result in severe stomach/intestinal issues (such as ulcers and bleeding). Deferasirox should not be taken if you have any of the unlikely but severe side effects listed below. Instead, stop using it and call your doctor or chemist right away. stomach/abdominal pain that won't go away, bloody or black faeces, and coffee-ground-like vomit.
Rarely, deferirox may result in serious (and perhaps fatal) liver damage. If you have any liver damage symptoms, such as persistent nausea or vomiting, appetite loss, stomach or abdominal pain, or yellowing of the skin or eyes, get immediate medical attention.
only severe (and occasionally fatal) kidney issues have only seldom been linked to deferirox. If you experience any kidney-related symptoms, such as changing the amount of urine you produce or foamy pee, contact your doctor straight once.
Deferasirox occasionally causes a rash, which is often not harmful. You might not be able to distinguish it from a rare rash, which could indicate a serious reaction. Immediately seek medical attention if you experience any rash.
Rarely will this medication cause a very serious allergic reaction. However, if you experience any major adverse reaction symptoms, such as a rash, itching or swelling (particularly of the face, tongue, or throat), severe dizziness, or difficulty breathing, seek medical attention right away.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Drug Interactions of Deferasirox :
Drug interactions could alter how your medications function or raise the possibility of major negative side effects. All probable medication interactions are not included in this document. Keep a list of everything you use, including herbal products, prescription and over-the-counter medications, and provide it to your doctor and chemist. Without your doctor's approval, never start, stop, or change the dosage of any medications.
Fezolinetant and other medications that might induce bleeding or bruising (such as antiplatelet medications like clopidogrel, NSAIDs like ibuprofen/naproxen, and "blood thinners" like dabigatran/warfarin) are a few examples of goods that may interact with this medication.
When used with this drug, aspirin can raise the risk of bleeding. But if your doctor has advised you to take low-dose aspirin (about 81–162 milligrammes a day) to prevent heart attacks or strokes, you should keep doing so unless your doctor gives you another order. For more information, speak to your doctor or chemist.
The effectiveness of hormonal birth control methods like pills, patches, or rings may be reduced by this medicine. Pregnancy could result from this. If you have any questions about whether you should use dependable backup birth control while taking this medicine, ask your doctor or pharmacist. Additionally, let your doctor know if you experience any new bleeding or spotting, as these could be indications that your birth control is not functioning properly.
Missed dose of Deferasirox :
If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.
Over dose of Deferasirox :
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call a poison control center right away.
Storage of Deferasirox :
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Additional information for Deferasirox :
DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children. IF YOU WILL BE TAKING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, be sure to obtain necessary refills before your supply runs out.
Cost of Deferasirox :
The lowest MyGenericPharmacy.com price for the most common version of Jadenu (Deferasirox) is around $2.65, 49% off the average online retailing price of $158.10.
MISSPELLINGS OF DEFERASIROX :
Jadeno, Jadenue, Jadenou, Jadinu, Jadenoo, Jadenux, Jadenyu, Jadano,
Jadinu, Jadenou, Jadennu, Jadenoo, Jadenew, Jadini, Deferasirox, Deferasiro, Deferoxamine, Deferoxir, Deferazirox, Deferaziron, Deferasirx, Deferasix,
Defersirox Deferasirox, Deferasix, Deferosirox, Deferasrox, Deferasorx,
Deferasirox, Defarasirox, Dferasirox, Deferasirix.
Generic Jadenu® : Deferasirox
Deferasirox is the chemical name of the active ingredient in Jadenu®
Generic Buy Jadenu™ 500 mg for Iron overload
Buy online Generic Jadenu (tm) 500 mg (30 Pills), Jadenu Cost, Price $79.50 at 49% Discount.
Other name brands for this medication
Exjade, Jadenu Sprinkle, Defrijet, Desirox, Asunra, Oleptiss, Deferataj, Deferglob, Ferasiro, Thalep
Possible Uses of Deferasirox :
This drug is used to treat persistently high iron levels in the body brought on by repeated blood transfusions. Additionally, it is used to treat non-transfusion-dependent thalassemia, a blood condition in which individuals have high iron levels but do not require blood transfusions. By attaching to iron, it causes the body to excrete excess iron in the stool. Deferasirox is a member of the group of medications known as iron-chelating agents.In some blood illnesses (such sickle cell disease and anaemia), frequent blood transfusions are frequently required. Blood transfusions have a lot of positive effects, but they can also make the body retain too much iron. The additional iron can accumulate in the body and lead to issues including diabetes, liver disease, and heart failure. The chance of developing these disorders can be reduced by getting rid of superfluous iron.
Before using Deferasirox :
Before taking deferasirox, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
How to take Deferasirox :
Before beginning to take deferasirox and each time you obtain a refill, read the medication guide that your chemist has provided. Ask your physician or chemist if you have any questions.
As prescribed by your doctor, often once daily, take this medication by mouth on an empty stomach or with a light meal (such as a whole-wheat english muffin with jelly and nonfat milk). Avoid taking this medication with a meal that has a lot of calories and fat (more than 250 calories), since it could make you more susceptible to side effects. For more information, speak to your doctor or chemist.
With water or other liquids, take the pills. If the tablets are difficult for you to swallow, you can smash them and mix them with soft foods (such yoghurt or applesauce). As soon as possible, swallow the entire drug/food combo. Don't make a supply ahead of time.
If you're using sprinkle granules, sprinkle the recommended dosage on soft food (such applesauce or yoghurt) and consume it all at once.
Deferasirox may bind to aluminum-containing antacids, which may change how effective deferasirox is. Do not combine this medication with aluminum-containing antacids.
To reap the greatest benefits from this drug, take it frequently. Take it at the same time every day to aid in memory. usage this medication just as directed and never up the dosage, frequency, or duration of usage. Your condition won't get better any faster, and your chance of experiencing negative effects will rise.
The dosage is determined by your medical history, weight, laboratory results, and treatment response. If you have specific side effects, your dosage may need to be reduced or your therapy may need to be stopped. Carefully adhere to your doctor's directions.
Precautions When Using Deferasirox :
If you have a medical history of renal illness, liver disease, low platelet counts, advanced cancer, or certain bone marrow problems involving damaged blood-forming cells (high-risk myelodysplastic syndromes), be sure to let your doctor or chemist know before taking this drug.
You can feel lightheaded or have blurry vision if you take this medication. You may feel more lightheaded after consuming alcohol or cannabis. Until you can do something safely, avoid using machinery, driving, or doing anything else that requires attentiveness or sharp vision. Limit your alcohol consumption. If you use marijuana (cannabis), speak with your doctor.
Inform your surgeon or dentist about all the products you use, including prescription, over-the-counter, and herbal medications.
If you experience any illness (such as a fever, diarrhoea, or vomiting) that could lead to dehydration or if you are unable to consume fluids, call your doctor straight once. Particularly in children, the doctor may need to discontinue or modify the deferasirox regimen.
Children may be more vulnerable to this medication's negative effects, including renal issues and hearing loss.
The adverse effects of this medication, particularly liver issues, stomach/intestinal bleeding, and ulcers, may be more severe in older persons.
If you are pregnant or want to become pregnant, let your doctor know. Deferasirox use should not be used with pregnancy. Deferasirox might be harmful to an unborn child. Consult your doctor as soon as possible about the dangers and advantages of this drug if you find out you're pregnant.
It is unknown if this medication passes into breast milk. Because of the possible risk to the infant, breast-feeding while using this medication is not recommended. Consult your doctor before breast-feeding.
Side Effects of Deferasirox :
There could be nausea, vomiting, diarrhoea, or lightheadedness. Inform your doctor or chemist as soon as possible if any of these side effects persist or get worse.
Keep in mind that your doctor has recommended this medication because they believe it will benefit you more than it will harm you. Many users of this medicine report no significant negative effects.
If you experience any severe adverse effects, such as hearing loss or vision abnormalities (such as impaired vision), call your doctor straight away.
Due to the medication's decreased bone marrow function, there may be fewer red, white, and platelet blood cells in the body. This effect may make anaemia worse, reduce your body's capacity to fight an infection, or make you more prone to bleeding and bruising. If you experience any of the following unlikely symptoms, contact your doctor straight away: Unusual fatigue, pale skin, infection-related symptoms (such as a persistent sore throat, fever, and chills), and easy bruising and bleeding.
Rarely, this medication may result in severe stomach/intestinal issues (such as ulcers and bleeding). Deferasirox should not be taken if you have any of the unlikely but severe side effects listed below. Instead, stop using it and call your doctor or chemist right away. stomach/abdominal pain that won't go away, bloody or black faeces, and coffee-ground-like vomit.
Rarely, deferirox may result in serious (and perhaps fatal) liver damage. If you have any liver damage symptoms, such as persistent nausea or vomiting, appetite loss, stomach or abdominal pain, or yellowing of the skin or eyes, get immediate medical attention.
only severe (and occasionally fatal) kidney issues have only seldom been linked to deferirox. If you experience any kidney-related symptoms, such as changing the amount of urine you produce or foamy pee, contact your doctor straight once.
Deferasirox occasionally causes a rash, which is often not harmful. You might not be able to distinguish it from a rare rash, which could indicate a serious reaction. Immediately seek medical attention if you experience any rash.
Rarely will this medication cause a very serious allergic reaction. However, if you experience any major adverse reaction symptoms, such as a rash, itching or swelling (particularly of the face, tongue, or throat), severe dizziness, or difficulty breathing, seek medical attention right away.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Drug Interactions of Deferasirox :
Drug interactions could alter how your medications function or raise the possibility of major negative side effects. All probable medication interactions are not included in this document. Keep a list of everything you use, including herbal products, prescription and over-the-counter medications, and provide it to your doctor and chemist. Without your doctor's approval, never start, stop, or change the dosage of any medications.
Fezolinetant and other medications that might induce bleeding or bruising (such as antiplatelet medications like clopidogrel, NSAIDs like ibuprofen/naproxen, and "blood thinners" like dabigatran/warfarin) are a few examples of goods that may interact with this medication.
When used with this drug, aspirin can raise the risk of bleeding. But if your doctor has advised you to take low-dose aspirin (about 81–162 milligrammes a day) to prevent heart attacks or strokes, you should keep doing so unless your doctor gives you another order. For more information, speak to your doctor or chemist.
The effectiveness of hormonal birth control methods like pills, patches, or rings may be reduced by this medicine. Pregnancy could result from this. If you have any questions about whether you should use dependable backup birth control while taking this medicine, ask your doctor or pharmacist. Additionally, let your doctor know if you experience any new bleeding or spotting, as these could be indications that your birth control is not functioning properly.
Missed dose of Deferasirox :
If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.
Over dose of Deferasirox :
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call a poison control center right away.
Storage of Deferasirox :
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Additional information for Deferasirox :
DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children. IF YOU WILL BE TAKING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, be sure to obtain necessary refills before your supply runs out.
Cost of Deferasirox :
The lowest MyGenericPharmacy.com price for the most common version of Jadenu (Deferasirox) is around $2.65, 49% off the average online retailing price of $158.10.
MISSPELLINGS OF DEFERASIROX :
Jadeno, Jadenue, Jadenou, Jadinu, Jadenoo, Jadenux, Jadenyu, Jadano,
Jadinu, Jadenou, Jadennu, Jadenoo, Jadenew, Jadini, Deferasirox, Deferasiro, Deferoxamine, Deferoxir, Deferazirox, Deferaziron, Deferasirx, Deferasix,
Defersirox Deferasirox, Deferasix, Deferosirox, Deferasrox, Deferasorx,
Deferasirox, Defarasirox, Dferasirox, Deferasirix.
FAQ
1. What is Deferasirox and its use?
Deferasirox is a medical drug that belongs to a class of medicine called Iron chelators. In patients with thalassemia syndromes that are not transfusion dependent as well as those who have received an excessive number of blood transfusions, deferasirox is used to eliminate extra iron from the body.
2. What is the mode of action of deferasirox?
A chelator of iron is deferasirox. Deferasirox works by inducing the cytochrome P450 3A4 enzyme, inhibiting the cytochrome P450 2C8 enzyme, and activating the cytochrome P450 1A2 enzyme.
3. How much iron does deferasirox remove?
Deferirox lowered the iron level of the heart by 20.5%. Myocyte hypertrophy, fibrosis, weight-to-dry weight ratio, or heart weight did not alter.
4. Can deferasirox damage the liver?
To treat iron excess brought on by transfusions, deferasirox, an oral iron chelator, is given once daily. Children with transfusion-dependent thalassemia (TDT) who were receiving deferasirox experienced hyperammonemia and acute liver failure (ALF).
5. When is the best time to take deferasirox?
The tablet and granules should be taken at the same time every day, preferably on an empty stomach or with a small meal. It is advisable to take the suspension tablet on an empty stomach, at least 30 minutes before you eat, at the same time every day. Use water, apple juice, or orange juice to dissolve the tablet for suspension.
6. What is the duration of action of deferasirox?
Deferasirox was found to have a prolonged effect for 33 hours following dosages of 50 mg/kg and 100 mg/kg and 30 hours after doses of 25 mg/kg and 50 mg/kg, respectively.
7. What are the side effects of deferasirox?
With this medication, serious skin responses can happen. If you or your kid has blistering, peeling, or red skin rash, red skin lesions, severe acne or skin rash, skin sores or ulcers, fever, or chills while taking this medication, consult your doctor immediately once.
