Helps control blood sugar levels, regulates the levels of insulin your body produces after eating.
Generic Januvia® : Sitagliptin Phosphate
Januvia™ 25Mg
Chemical Name: Sitagliptin Phosphate
Generic Buy Januvia™ 25 mg (30 Pills) for Diabetes
Buy online Generic Januvia (tm) 25 mg (30 Pills), Januvia Cost, Price $82.50 at 35% Discount.
Other name brands for this medication
Jenuvia is a common misspelling of Januvia (sitagliptin)
Zituvio, Auro-Sitagliptin, JAMP Sitagliptin, Istavel, Siglipol, Lupisit, Sitabetic, Sitacot
DRUG DESCRIPTION
Januvia Tablets contain sitagliptin phosphate, an orally-active inhibitor of the dipeptidyl peptidase-4 (DPP-4) enzyme. Sitagliptin phosphate monohydrate is described chemically as 7-[(3R)-3-amino-1-oxo-4-(2,4,5trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine phosphate (1:1) monohydrate. The empirical formula is C16H15F6N5O•H3PO4•H2O and the molecular weight is 523.32
Generic Januvia™ 25mg
Chemical Name: sitagliptin phosphate
Before using Januvia:
It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine.
How to take Januvia:
Recommended Dosing: The recommended dose of JANUVIA is 100 mg once daily. JANUVIA can be taken with or without food.
Patients with Renal Insufficiency: For patients with mild renal insufficiency (creatinine clearance [CrCl] greater than or equal to 50 mL/min, approximately corresponding to serum creatinine levels of less than or equal to 1.7 mg/dL in men and less than or equal to 1.5 mg/dL in women), no dosage adjustment for JANUVIA is required.
For patients with moderate renal insufficiency (CrCl greater than or equal to 30 to less than 50 mL/min, approximately corresponding to serum creatinine levels of greater than 1.7 to less than or equal to 3.0 mg/dL in men and greater than 1.5 to less than or equal to 2.5 mg/dL in women), the dose of JANUVIA is 50 mg once daily.
For patients with severe renal insufficiency (CrCl less than 30 mL/min, approximately corresponding to serum creatinine levels of greater than 3.0 mg/dL in men and greater than 2.5 mg/dL in women) or with end-stage renal disease (ESRD) requiring hemodialysis or peritoneal dialysis, the dose of JANUVIA is 25 mg once daily. JANUVIA may be administered without regard to the timing of dialysis.
Because there is a need for dosage adjustment based upon renal function, assessment of renal function is recommended prior to initiation of JANUVIA and periodically thereafter. There have been postmarketing reports of worsening renal function in patients with renal insufficiency, some of whom were prescribed inappropriate doses of sitagliptin.
Concomitant Use with an Insulin Secretagogue (e.g., Sulfonylurea) or with Insulin
When JANUVIA is used in combination with an insulin secretagogue (e.g., sulfonylurea) or with insulin, a lower dose of the insulin secretagogue or insulin may be required to reduce the risk of hypoglycemia.
Precautions When Using Januvia:
Before taking sitagliptin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, disease of the pancreas (pancreatitis).
You may experience blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar levels. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely.
Limit alcohol while taking this medication because it can increase your risk of developing low blood sugar.
It may be harder to control your blood sugar when your body is stressed (such as due to fever, infection, injury, or surgery). Consult your doctor because increased stress may require a change in your treatment plan, medications, or blood sugar testing.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
During pregnancy this medication should be used only when clearly needed. Pregnancy may cause or worsen diabetes. Discuss a plan with your doctor for managing your blood sugar while pregnant. Your doctor may change your diabetes treatment during your pregnancy. Discuss the risks and benefits of different treatments (such as diet, exercise, and medications including insulin).
It is unknown whether this drug passes into breast milk. Consult your doctor before breast-feeding.
Side Effects of Januvia:
Some side effects of sitagliptin may not be reported. Always consult your doctor or healthcare expert for medical advice.
Get emergency medical help if you have any of these signs of an allergic reaction while taking sitagliptin: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using sitagliptin and call your doctor at once if you have:
• pancreatitis - severe pain in your upper stomach spreading to your back, nausea and vomiting, loss of appetite, fast heart rate;
• little or no urinating;
• swelling, weight gain, feeling short of breath; or
• severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Common side effects may include:
• runny or stuffy nose, sore throat;
• headache, back pain, joint or muscle pain; or
• nausea, stomach pain, diarrhea, constipation.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Drug Interactions of Januvia:
Drug interactions can result in unwanted side effects or prevent a medicine from doing its job.
Digoxin:
There was a slight increase in the area under the curve (AUC, 11%) and mean peak drug concentration (Cmax, 18%) of digoxin with the co-administration of 100 mg sitagliptin for 10 days. Patients receiving digoxin should be monitored appropriately. No dosage adjustment of digoxin or JANUVIA is recommended
Overdose of Januvia:
IF OVERDOSE IS SUSPECTED, contact your local poison control center or emergency room immediately.
Other Information of Januvia:
If your symptoms do not improve with regular use of this medicine or if they become worse, check with your doctor. ALWAYS HAVE A SPARE CONTAINER available in case the unit malfunctions or is empty. DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children. IF YOU WILL BE USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, be sure to obtain necessary refills before your supply runs out.
COST OF Januvia : The lowest MyGenericPharmacy.com price for the most common version of Januvia (Sitagliptin) is around $2.75, 35% off the average online retailing price of $127.50.
MISSPELLINGS OF JANUVIA :
Janvia, Januvvia, Janovia, Januviaa, Januvia, Januviva, Janvvia, Januviaa, Jannuvia, Januvya, Januviah, Janovia, Janouvia, Januviah, Januvea, Januvya,
Janoviaa, Sitaglipin, Sitaglipten, Sitagliptin, Sitagliten, Sitagliptine, Sitaglipten, Sitaglipten, Sitagliptan, Sitagliptim, Sitagliptin, Sitagliptan, Sitaglipton,
Sitaglipteen, Sittaglipton.
Helps control blood sugar levels, regulates the levels of insulin your body produces after eating.
Generic Januvia® : Sitagliptin Phosphate
Januvia™ 25Mg
Chemical Name: Sitagliptin Phosphate
Generic Buy Januvia™ 25 mg (30 Pills) for Diabetes
Buy online Generic Januvia (tm) 25 mg (30 Pills), Januvia Cost, Price $82.50 at 35% Discount.
Other name brands for this medication
Jenuvia is a common misspelling of Januvia (sitagliptin)
Zituvio, Auro-Sitagliptin, JAMP Sitagliptin, Istavel, Siglipol, Lupisit, Sitabetic, Sitacot
DRUG DESCRIPTION
Januvia Tablets contain sitagliptin phosphate, an orally-active inhibitor of the dipeptidyl peptidase-4 (DPP-4) enzyme. Sitagliptin phosphate monohydrate is described chemically as 7-[(3R)-3-amino-1-oxo-4-(2,4,5trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine phosphate (1:1) monohydrate. The empirical formula is C16H15F6N5O•H3PO4•H2O and the molecular weight is 523.32
Generic Januvia™ 25mg
Chemical Name: sitagliptin phosphate
Before using Januvia:
It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine.
How to take Januvia:
Recommended Dosing: The recommended dose of JANUVIA is 100 mg once daily. JANUVIA can be taken with or without food.
Patients with Renal Insufficiency: For patients with mild renal insufficiency (creatinine clearance [CrCl] greater than or equal to 50 mL/min, approximately corresponding to serum creatinine levels of less than or equal to 1.7 mg/dL in men and less than or equal to 1.5 mg/dL in women), no dosage adjustment for JANUVIA is required.
For patients with moderate renal insufficiency (CrCl greater than or equal to 30 to less than 50 mL/min, approximately corresponding to serum creatinine levels of greater than 1.7 to less than or equal to 3.0 mg/dL in men and greater than 1.5 to less than or equal to 2.5 mg/dL in women), the dose of JANUVIA is 50 mg once daily.
For patients with severe renal insufficiency (CrCl less than 30 mL/min, approximately corresponding to serum creatinine levels of greater than 3.0 mg/dL in men and greater than 2.5 mg/dL in women) or with end-stage renal disease (ESRD) requiring hemodialysis or peritoneal dialysis, the dose of JANUVIA is 25 mg once daily. JANUVIA may be administered without regard to the timing of dialysis.
Because there is a need for dosage adjustment based upon renal function, assessment of renal function is recommended prior to initiation of JANUVIA and periodically thereafter. There have been postmarketing reports of worsening renal function in patients with renal insufficiency, some of whom were prescribed inappropriate doses of sitagliptin.
Concomitant Use with an Insulin Secretagogue (e.g., Sulfonylurea) or with Insulin
When JANUVIA is used in combination with an insulin secretagogue (e.g., sulfonylurea) or with insulin, a lower dose of the insulin secretagogue or insulin may be required to reduce the risk of hypoglycemia.
Precautions When Using Januvia:
Before taking sitagliptin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, disease of the pancreas (pancreatitis).
You may experience blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar levels. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely.
Limit alcohol while taking this medication because it can increase your risk of developing low blood sugar.
It may be harder to control your blood sugar when your body is stressed (such as due to fever, infection, injury, or surgery). Consult your doctor because increased stress may require a change in your treatment plan, medications, or blood sugar testing.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
During pregnancy this medication should be used only when clearly needed. Pregnancy may cause or worsen diabetes. Discuss a plan with your doctor for managing your blood sugar while pregnant. Your doctor may change your diabetes treatment during your pregnancy. Discuss the risks and benefits of different treatments (such as diet, exercise, and medications including insulin).
It is unknown whether this drug passes into breast milk. Consult your doctor before breast-feeding.
Side Effects of Januvia:
Some side effects of sitagliptin may not be reported. Always consult your doctor or healthcare expert for medical advice.
Get emergency medical help if you have any of these signs of an allergic reaction while taking sitagliptin: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using sitagliptin and call your doctor at once if you have:
• pancreatitis - severe pain in your upper stomach spreading to your back, nausea and vomiting, loss of appetite, fast heart rate;
• little or no urinating;
• swelling, weight gain, feeling short of breath; or
• severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Common side effects may include:
• runny or stuffy nose, sore throat;
• headache, back pain, joint or muscle pain; or
• nausea, stomach pain, diarrhea, constipation.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Drug Interactions of Januvia:
Drug interactions can result in unwanted side effects or prevent a medicine from doing its job.
Digoxin:
There was a slight increase in the area under the curve (AUC, 11%) and mean peak drug concentration (Cmax, 18%) of digoxin with the co-administration of 100 mg sitagliptin for 10 days. Patients receiving digoxin should be monitored appropriately. No dosage adjustment of digoxin or JANUVIA is recommended
Overdose of Januvia:
IF OVERDOSE IS SUSPECTED, contact your local poison control center or emergency room immediately.
Other Information of Januvia:
If your symptoms do not improve with regular use of this medicine or if they become worse, check with your doctor. ALWAYS HAVE A SPARE CONTAINER available in case the unit malfunctions or is empty. DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children. IF YOU WILL BE USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, be sure to obtain necessary refills before your supply runs out.
COST OF Januvia : The lowest MyGenericPharmacy.com price for the most common version of Januvia (Sitagliptin) is around $2.75, 35% off the average online retailing price of $127.50.
MISSPELLINGS OF JANUVIA :
Janvia, Januvvia, Janovia, Januviaa, Januvia, Januviva, Janvvia, Januviaa, Jannuvia, Januvya, Januviah, Janovia, Janouvia, Januviah, Januvea, Januvya,
Janoviaa, Sitaglipin, Sitaglipten, Sitagliptin, Sitagliten, Sitagliptine, Sitaglipten, Sitaglipten, Sitagliptan, Sitagliptim, Sitagliptin, Sitagliptan, Sitaglipton,
Sitaglipteen, Sittaglipton.
FAQ
1. What is Sitagliptin and what is it used for?
Sitagliptin is a medical drug which belongs to a class of medication called dipeptidyl peptidase-4 (DPP-4) inhibitors. This medicine is used alone or as a combination with other medicine to treat type 2 diabetes mellitus by controlling the glucose level of blood in the body with a proper diet and exercise. This kind of diabetes is also called maturity onset diabetes.
2. When and how to use Sitagliptin?
Sitagliptin is available to us in a form of pill that must be taken by mouth with or without food as per your doctor's prescription. It is usually taken once a day daily. The dosage is based on your medical condition, kidney function and its response to the treatment. Your doctor may start your medication with a low dosage so that the risk of side effects gets reduced. Your doctor may also vary your dosage depending upon the blood sugar level of your body. Take this medicine at the same time daily to get the most benefits from it. you must inform your doctor if you notice any change in your blood sugar level. Discuss all the other medicine that you may be taking along with Glucovance so that your doctor may need to adjust your dosage accordingly. Read the leaflet instruction carefully and consult your doctor in case of any confusion.
3. What are the side effects of Sitagliptin?
Common side effects observed while medicating with Sitagliptin is low blood sugar may occur. Inform your doctor if this condition persists or gets worse. There are some severe side effects which must be informed to the doctor right away if observed such as signs of kidney problems (such as change in the amount of urine), joint pain, unusual skin blisters, signs of heart failure (such as shortness of breath, swelling ankles/feet, unusual tiredness, unusual/sudden weight gain), symptoms of low blood sugar include sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or tingling hands/feet, symptoms of high blood sugar (hyperglycemia) include thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, and fruity breath odor, constipation, blood/mucus in stool etc. There are also some rare but serious allergic reactions to this medicine which requires immediate medical attention if observed such as severe dizziness, trouble breathing, rash, itching/swelling, signs of pancreatitis(such as persistent nausea/vomiting, loss of appetite, severe stomach/abdominal/back pain) etc.
4. How effective is Sitagliptin?
Sitagliptin is considered as an effective, well tolerated and safe medicine for the treatment of type 2 diabetes mellitus when used as a monotherapy or as a combination with other medical agents. It has proven to reduce the conversion rate of food into glucose thereby reducing the blood sugar level and also improves the function of a kind of cell found in pancreas that produces insulin.
5. How long does it take for sitagliptin to work?
Sitagliptin is a kind of medicine that works quickly. You may observe some noticeable sugar level drop just after a few doses. However, the actual effect of sitagliptin on your blood sugar level may initialize within 1-2 weeks of regular medication with proper diet and exercise if possible as these factors also play an important role in effectiveness of this medicine.
6. What precautions must be taken before medicating with Sitagliptin?
Before the onset of Sitagliptin medication, you must inform your doctor regarding certain conditions such as allergies related to it, or any other allergies as these products may contain some ingredient that causes an allergic reaction inside your body. Tell your doctor if you have any medical history related to kidney problems or disease, liver disease, stone in the gallbladder, disease of the pancreas, etc. Before undergoing any kind of surgery, inform the doctor regarding all the products that you use including prescribed, herbal and non-prescribed.
7. Is Sitagliptin safe during pregnancy?
Sitagliptin is a kind of medicine that must only be used when necessary during pregnancy. Pregnancy may worsen the diabetes condition and your doctor may need to reschedule the treatment and its course. Discuss the risk and benefits before medicating with Sitagliptin. Also, it is unknown whether the drug gets passed into breast milk or not.
8. Is Sitagliptin the same as metformin?
Sitagliptin and Metformin, both the medicine has proven to be effective in treating diabetes. Metformin works by decreasing the production of glucose in the liver and absorption of glucose in the intestine. Sitagliptin regulates the amount of insulin your body produces after the intake of food.
