Buy Generic Kytril (Granisetron) Online

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About Generic Kytril® (Granisetron)

Key Details

1. Generic Kytril™ 1 mg for Cancer
2. Buy online Generic Kytril™ 1mg (20 Pills), Kytril Cost, Price $40.00 at 90% Discount
3. Prevents chemotherapy-induced nausea and vomiting
4. Effective for radiotherapy-induced nausea
5. Well tolerated

How Generic Kytril Works

Generic Kytril prevents nausea by blocking serotonin released from enterochromaffin cells in the gut during chemotherapy or radiation. This stops stimulation of vagal afferent nerves that trigger vomiting.

It also acts centrally at the chemoreceptor trigger zone and vomiting center in the brain. This dual peripheral and central action makes it highly effective for acute nausea and vomiting.

Drug Info

GRANISETRON– ORAL (gran ih SE tron)
Common Brand Name(s): Kytril™

Other name brands for this medication
Sustol, Granisol, Sancuso, Graniforce, Grandem, Graniset, Granicip, Granitero, Granirex, Cadigran, Emegran 3, Granexa

Uses of Kytril

This medication is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy). It is also used to prevent and treat nausea and vomiting after surgery in adults.

Granisetron belongs to a class of medications called 5-HT3 blockers. It works by blocking one of the body's natural substances (serotonin) that can cause vomiting.

Before Using Kytril

Before using granisetron, tell your doctor or pharmacist if you are allergic to it; or to other 5-HT3 blockers (e.g., dolasetron, ondansetron); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.  

How to Use Kytril

Read the Patient Information Leaflet if available from your pharmacist before you start using granisetron and each time you get a refill. If you have any questions, ask your doctor or pharmacist. This drug is given into a vein as directed by your doctor, usually 30 minutes before cancer chemotherapy or before/during/after surgery. The drug may be given directly into a vein over 30 seconds, or it may be mixed in an IV fluid and given into a vein over a longer time (5 minutes).

If you are giving this medication to yourself at home, learn all preparation and usage instructions from your health care professional. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely. Do not mix granisetron with other drugs in the same injection or inject other drugs into the same vein at the same time. If you have questions about using this medication properly, consult your pharmacist.

Dosage is based on your medical condition and response to treatment. The dosage may also be based on weight. Use this medication exactly as directed to get the most benefit from it. Do not use more medication or use it more often than prescribed. Ask your doctor or pharmacist if you have questions. Tell your doctor if your nausea does not improve or if it worsens.

Side Effects of Kytril

Headache, diarrhea, dizziness, fever, or pain/redness/swelling at the injection site may occur. If any of these effects persist or worsen, tell your doctor promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: stomach/abdominal pain. Get medical help right away if any of these rare but serious side effects occur: chest pain, fast/irregular heartbeat, severe dizziness, fainting.

This medication may increase serotonin and rarely cause a very serious condition called serotonin syndrome/toxicity. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take (see Drug Interactions section). Get medical help right away if you develop some of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, unusual agitation/restlessness.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

Before using this medication, tell your doctor or pharmacist your medical history, especially of: stomach/intestinal problems (e.g., recent surgery, ileus, swelling). This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.

Granisetron may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can infrequently result in serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away. The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using granisetron, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).

Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using granisetron safely. Older adults may be more sensitive to the side effects of this drug, especially QT prolongation (see above).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.

Drug Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: apomorphine. Many drugs besides granisetron may affect the heart rhythm (QT prolongation), including amiodarone, dofetilide, pimozide, procainamide, quinidine, sotalol, macrolide antibiotics (such as erythromycin), among others.

The risk of serotonin syndrome/toxicity increases if you are also taking other drugs that increase serotonin. Examples include street drugs such as MDMA/"ecstasy," St. John's wort, certain antidepressants (including SSRIs such as fluoxetine/paroxetine, SNRIs such as duloxetine/venlafaxine), among others. The risk of serotonin syndrome/toxicity may be more likely when you start or increase the dose of these drugs.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Overdose

If overdose is suspected, contact a poison control center or emergency room immediately.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Cost of Kytril

The lowest MyGenericPharmacy.com price for the most common version of Kytril (Granisetron) is around $2.00, 90% off the average online retailing price of $405.60.

What is Kytril / Granisetron?
Kytril is an antiemetic medication used to prevent and treat nausea and vomiting associated with chemotherapy, radiotherapy, and surgery. It is particularly effective for chemotherapy-induced nausea and vomiting (CINV).

How Does Kytril Work?
Granisetron is a selective 5-HT₃ (serotonin) receptor antagonist. It blocks serotonin receptors in the gastrointestinal tract and central nervous system, preventing activation of the vomiting reflex.

Benefits of Kytril

1. Prevents chemotherapy-induced nausea and vomiting
2. Effective for radiotherapy-induced nausea
3. Useful for postoperative nausea and vomiting
4. Well tolerated
5. Minimal sedation

Dosage & How to Use

1. Taken orally or intravenously
2. Oral dose: 1 mg twice daily or 2 mg once daily
3. IV dose: 1 mg before chemotherapy
4. Administer before chemotherapy or surgery
5. Dose adjustment in severe hepatic impairment

Side Effects & Precautions
Common side effects may include:

1. Headache
2. Constipation
3. Dizziness
4. Fatigue

Precautions:

1. Use caution in patients with cardiac rhythm disorders
2. Monitor ECG in high-risk patients
3. Avoid combination with other QT-prolonging drugs
4. Use caution with serotonergic medications

Who Should Not Take Kytril

1. Hypersensitivity to granisetron
2. Known QT prolongation or serious arrhythmias
3. Concomitant use with QT-prolonging drugs (use caution)
4. Severe hepatic impairment (dose adjustment required)

Other Information of Kytril :
DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.

MISSPELLINGS OF KYTRIL :
Kytiril, Kytrill, Kytrol, Kytrol, Kytrilz, Kytrilx, Kytriln, Kytirl, Kytrille, Kyttril, Kyttrilz, Kytrillz, Kytroil, Kytrilv, Kytrel, Kitrel, Kytrel, Kitril, Kytrol, Kyteril, Kytrel,  Granistron, Granisetronn, Granisetrone, Grannisetron, Granisetrin, Granisetronx, Granistrom, Granestron, Granisetorn, Granisotron, Granishtron, Granisetronne, Granisetroan, Granisetrone, Grannisetron, Granistaron, Granisettron, 
Granesetron, Granisetran, Granitsetron, Grannisotron.

FAQ

1. What is Granisetron (Kytril) and what is it used for?
Granisetron is a medical drug sold under the brand name Kytril which belongs to a class of medication called 5-HT3 receptor antagonists. This medicine is used alone or as a combination with other medical agents to prevent vomiting and nausea caused by cancer chemotherapy and radiation therapy.

2. When and how to use Granisetron?
Granisetron is available to us in a form of medicine that must be taken by mouth with or without food as per your doctor's prescription. It must be swallowed by mouth with plenty of water rather than chewing or crushing it. The number of doses must be confirmed by the doctor as the dosage is based on your medical condition, weights and illness response. Also the timeline for each dosage may vary. It is recommended for you to follow the medical prescription carefully. Discuss all the details regarding the medicine and its medication with your doctor.

3. What are the side effects of Granisetron?
Common side effects observed while medicating with Granisetron are Diarrhea, vomiting, headache, drowsiness, constipation, fever, trouble sleeping, dizziness and anxiety may occur. Inform your doctor if these conditions persist or get worse. There are some severe side effects which must be informed to the doctor right away if observed like , fast/irregular heartbeat, severe dizziness, fainting, chest pain. There are also some allergic side effects which occur rarely but must get immediate medical attention such as severe dizziness, rash, trouble breathing, itching/swelling etc.

4. What is serotonin toxicity/syndrome?
Granisetron medication may lead to an increase in level of serotonin(a substance in the body that enables brain cells and other nervous system cells to communicate with each other). Also there is a risk of increase if you are taking other drugs which may trigger it. You must get medical attention right away if you notice symptoms of serotonin toxicity such as severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, unusual agitation/restlessness, heartbeat, hallucination, loss of coordination etc.

5. How long does Granisetron take to work?
The effectiveness of medicine may vary depending upon the kind of illness treated. However, Granisetron is taken 1 hour before chemotherapy if it causes nausea, vomiting etc. A second dose may be taken usually 12 hours after the first dose depending upon condition.

6. Is Granisetron safe in pregnancy?
Few medical guidelines suggest that Granisetron is an optional medicine for treatment of nausea and vomiting in women who are pregnant. The reason for this consideration is due to lack of medical support for fetal safety.

7. Is granisetron better than ondansetron?
Granisetron at an intravenous dose of 2 mg became determined to be safe, properly tolerated, and extra powerful by way of growing the occurrence of whole response compared to 4 mg intravenous ondansetron while used for antiemetic prophylaxis in maxillofacial surgical procedure patients receiving trendy anesthesia.

8. What is the mechanism of action of granisetron?
Granisetron is an indazole spinoff with antiemetic residences. As a selective serotonin receptor antagonist, granisetron competitively blocks the action of serotonin at five-hydroxytryptamine3 (5-HT3) receptors, resulting within the suppression of chemotherapy- and radiotherapy-caused nausea and vomiting.