Buy Generic Otezla (Apremilast) Online

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About Generic Otezla® (Apremilast)

Key Details

1. Generic Otezla™ 30mg for Arthritis
2. Buy online Generic Otezla™ 30 mg (30 Pills), Otezla Cost, Price $40.30 at 26% Discount
3. Oral treatment—no injections needed
4. Reduces psoriasis plaques and itching
5. Improves joint pain and stiffness in psoriatic arthritis

How Generic Otezla Works

Generic Otezla (apremilast) works by inhibiting phosphodiesterase-4 (PDE-4), an enzyme responsible for breaking down cyclic AMP (cAMP) inside immune cells. By blocking PDE-4, cAMP levels increase, which leads to a reduction in the production of pro-inflammatory cytokines such as TNF-α, IL-17, and IL-23—key drivers of psoriasis and psoriatic arthritis. This helps decrease redness, flaking, plaque thickness, and joint inflammation.

In addition to reducing inflammatory cytokines, Otezla also increases the production of anti-inflammatory cytokines like IL-10, restoring a healthier immune balance. Because it acts selectively within immune pathways and does not suppress the entire immune system, Otezla has a lower infection risk compared to many biologics and immunosuppressants. Its oral tablet form also makes it a convenient long-term treatment option.

Drug Info

APREMILAST– ORAL (a PRE mil ast)
Common Brand Name(s): Otezla™

Other name brands for this medication
Aprezo, Aplex, Pdlast, Riasis, Apreno, Apraize, Apremist

Uses of Otezla

Apremilast is used to treat active psoriatic arthritis in adults. Apremilast is also used to treat moderate to severe plaque psoriasis in adults who may also receive phototherapy or other treatments for psoriasis. Apremilast is also used to treat mouth ulcers in adults with Behçet's disease (a disease causing inflammation in blood vessels).

Before Using Otezla

Before taking apremilast, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

How to Use Otezla

Take this medication by mouth with or without food as directed by your doctor, usually twice daily. The manufacturer directs not to crush, split, or chew the tablet before taking it. However, many similar drugs (immediate-release tablets) can be crushed, split, or chewed. Follow your doctor's directions on how to take this medication.

The dosage is based on your medical condition and response to treatment. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.

Tell your doctor if your condition does not improve or if it worsens.

Side Effects of Otezla

Diarrhea, nausea/vomiting, loss of appetite, headache, or weight loss may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: severe nausea/vomiting/diarrhea.

Rarely, people who take this medication may experience depression, suicidal thoughts/attempts, or other mental/mood problems. Tell your doctor right away if you or your family/caregiver notice any unusual/sudden changes in your mood, thoughts, or behavior including signs of depression, suicidal thoughts/attempts, thoughts about harming yourself.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, mental/mood disorders (such as depression).

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Consult your pharmacist or physician.
 

Drug Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Other medications can affect the removal of apremilast from your body, which may affect how apremilast works. Examples include certain drugs used to treat seizures (such as carbamazepine, phenobarbital, phenytoin, primidone), rifamycins (such as rifampin, rifabutin), among others.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Overdose

If overdose is suspected, contact a poison control center or emergency room immediately.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Cost of Otezla

The lowest MyGenericPharmacy.com price for the most common version of Otezla (Apremilast) is around $1.34, 26% off the average online retailing price of $54.90.

What is Otezla / Apremilast?
Otezla (apremilast) is an oral PDE-4 inhibitor used to treat plaque psoriasis, psoriatic arthritis, and Behçet’s disease-related mouth ulcers. It helps reduce inflammation, scaling, joint pain, and immune overactivity.

How Does Otezla Work?
Otezla blocks the PDE-4 enzyme, raising cAMP levels inside immune cells. This reduces inflammatory cytokines and increases anti-inflammatory signals, leading to improved skin and joint symptoms.

Benefits of Otezla

1. Oral treatment—no injections needed
2. Reduces psoriasis plaques and itching
3. Improves joint pain and stiffness in psoriatic arthritis
4. Helps mouth ulcers caused by Behçet’s disease
5. Low risk of serious infections
6. Does not require regular blood test monitoring
7. Works on inflammation at the cellular level
8. Steroid-free, non-immunosuppressive option

Dosage & How to Use
Maintenance Dose:

1. 30 mg twice daily (morning and evening)

General Use Tips:

1. Can be taken with or without food
2. Swallow tablets whole
3. Do not stop suddenly without consulting your doctor
4. Full effects may take 8–16 weeks

Side Effects & Precautions
Common side effects may include:

1. Diarrhea
2. Nausea
3. Headache
4. Weight loss
5. Abdominal discomfort
6. Fatigue

Precautions:

1. Monitor weight regularly
2. Tell your doctor about any new or worsening depression
3. Stay hydrated to reduce stomach side effects
4. Avoid use in severe kidney disease unless dose-adjusted
5. Not recommended during pregnancy unless essential

Who Should Not Take Otezla

1. Are allergic to apremilast
2. Have a history of severe depression or suicidal thoughts
3. Have end-stage kidney disease (without dose adjustment)
4. Are pregnant or planning pregnancy
5. Have unexplained, significant weight loss

Other Information of Otezla :
FOR BEST RESULTS, this medicine should be used along with exercise, a low-cholesterol/low-fat diet, and a weight loss program if you are overweight. FOLLOW THE DIETARY PLAN provided by your doctor. DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children and pets. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out

MISSPELLINGS OF OTEZLA :
Otezla, Otezlla, Otezla pill, Otezlaa, Otezlia, Otesla, Otezla medication, Otezlaa pill, Otezla tablets, Oteza, Otezlla pill, Otezla drug, Apremelist, Apremilast, Apremilaste, Apremilastt, Apremilats, Aprimilast, Apremilaat, Apremilst, Apremilist, Apremalast, Apremelast, Apremilaste.

FAQ

1. What is Apremilast and what is it used for?
Apremilast is a medical drug that belongs to a class of medication called phosphodiesterase inhibitors. The medicine is used to treat a certain type of skin condition called plaque psoriasis and is also used to treat psoriatic arthritis. It works by blocking mechanisms of certain natural substances in the body that cause inflammation.

2. When and how to use Apremilast?
Apremilast is available to us in a form of pill that must be taken by mouth with or without food as per your doctor's prescription. An ideal dose of one tablet twice a day daily is recommended. The dosage is based on your medical condition and its response to the treatment. Swallow the tablet whole rather than chewing or crushing it in your mouth. Take the medicine at the same time daily to get the most benefits from it. Follow the medical prescription carefully and consult a doctor in case of any confusion or exception.

3. What are the side effects of using Apremilast?
Common side effects observed while medicating with Apremilast are headache, weight loss, nausea, loss of appetite, diarrhea, vomiting, etc. Inform your doctor if these conditions persist or get worse. There are some serious side effects that must be informed to the doctor right away if observed such as signs of depression, mental/mood change, suicidal thoughts. There are also some severe allergic reactions involved with this medication that require immediate medical attention if observed such as severe dizziness, rash, trouble breathing, facial itching/swelling, etc.

4. What precautions must be taken before medicating with Apremilast?
Before mediating with Apremilast, one must inform the doctor regarding allergy to the medicine, its ingredient, or any other allergies. Inform your doctor regarding any medical history related to kidney diseases, mental/mood disorder etc. ALso, inform your doctor regarding all the drugs you may be taking before undergoing any surgery.

5. Can a pregnant woman use Apremilast?
Apremilast is a medical drug in a form of tablet that must only be used when clearly needed during pregnancy. One must consult a doctor before medicating with Apremilast during pregnancy.

6. Is Apremilast safe during breastfeeding?
It is unknown whether Apremilast gets passed on to the breast milk or not during its medication. Therefore, it is necessary to consult a doctor regarding the potential risk to the child from Apremilast before breastfeeding the baby.

7. Can apremilast cure psoriasis?
Apremilast is a new generation medicine that provides a robust treatment of psoriatic arthritis and psoriasis. Apremilast is the only medicine that does not require frequent medical tests during its medication like other strong medicines.

8. How long must Apremilast be taken?
Apremilast is a kind of medicine that could be used for a long period of time. One must observe significant improvement in their condition within 16 weeks. If no improvement is observed within this time period, your doctor may change the medicine for you.

9. Can you take Apremilast along with alcohol?
Apremilast is generally not known to cause any kind of liver damage when used with alcohol. However, certain other complications may arise in the meantime. Therefore, it is advisable to avoid alcohol while medicating with Apremilast.

10. Does Apremilast cause weight loss?
During medication with Apremilast, weight loss and loss of appetite are common side effects. An average of 10-12% of consumers could experience 5-10% loss of body weight. Some people may also observe more than 10% loss of weight.