Generic Sprycel™®: Dasatinib
Dasatinib is the chemical name of the active ingredient in Sprycel™®
Generic Buy Sprycel™ 20 mg (60 Pills) for Cancer
Buy online Generic Sprycel™ 20 mg (60 Pills), Sprycel Cost, Price $288.00 at 83% Discount.
Other name brands for this medication
Phyrago, Nextki, Beedan, Alsatinib, Leu Kinib, Dasapan, Dasamaps, Dasamyl, Dasanat, Dsatinib ML
Possible Uses of Dasatinib :
Certain forms of cancer are treated with this drug (chronic myeloid leukemia-CML, acute lymphoblastic leukemia-ALL). It inhibits or stops the development of cancer cells.
Before using Dasatinib :
Before taking dasatinib, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as lactose), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
How to take Dasatinib :
Before beginning to take dasatinib and each time you receive a refill, read the Patient Information Leaflet if it is available from your pharmacist. Ask your physician or pharmacist if you have any queries.
Take this medication by mouth once daily, generally with or without meal, as prescribed by your doctor. Completely swallow the tablets. The tablets must not be chewed, crushed, or broken.
The dosage is determined by your medical history, treatment response, lab results, and any additional medications you may be taking. The dosage for kids is also determined by weight. Inform your physician and pharmacist of all the products you consume (including prescription drugs, nonprescription drugs, and herbal products).
Usage this medication just as directed and never up the dosage, frequency, or duration of use. Your disease won't get better any faster, and you'll be at a higher risk for negative side effects.
Avoid ingesting antacids within two hours of taking this medication or immediately afterward since they will hinder your body from fully absorbing it. Examples of such antacids include aluminum/magnesium hydroxide and calcium carbonate.
If you're taking this medication, avoid eating or drinking grapefruit unless your doctor or pharmacist advises it's safe for you to. The likelihood of this medication's negative effects can be increased by grapefruit. For more information, speak to your doctor or pharmacist.
Women who are or may become pregnant should not handle this medication or breathe the dust from the pills since it can be absorbed through the skin and lungs and may harm an unborn child.
Precautions When Using Dasatinib :
Inform your doctor or pharmacist about your medical history before using this drug, especially of: bleeding issues, an ongoing or recent infection, heart issues (such as an irregular heartbeat), and liver issues (such as hepatitis B).
A disorder that alters the heart rhythm could be brought on by dasatinib (QT prolongation). Rarely, QT prolongation can result in fast/irregular heartbeat that is significant (rarely fatal) and other symptoms including acute dizziness and fainting that require immediate medical intervention.
If you take other medications or have certain medical problems that could raise your risk of QT prolongation, you should consult your doctor. Before taking dasatinib, inform your doctor or pharmacist of all the medications you take and any medical conditions you may have, such as certain heart conditions (heart failure, a slow heartbeat, an EKG finding called QT prolongation), a family history of certain heart conditions, and any of the following (QT prolongation in the EKG, sudden cardiac death).
Your risk of QT prolongation may also increase if your blood contains too little potassium or magnesium. This risk could rise if you take specific medications (such diuretics or "water pills") or experience symptoms like excessive sweating, diarrhoea, or vomiting. Ask your doctor for advice on how to use dasatinib safely.
Dasatinib may increase your risk of infection or exacerbate any existing infections. Stay away from persons who may be infected and infect others (such as chickenpox, measles, flu). If you have been exposed to an infection or would need additional information, speak with your doctor.
Before receiving any immunisations or vaccinations, let your doctor know that you are taking dasatinib. Avoid interacting with anyone who has just received a live vaccine (such as flu vaccine inhaled through the nose).
Avoid engaging in activities like contact sports and exercise caution while handling razors and other sharp devices, such as nail cutters.
The development and growth of a child's bones may be impacted by this medicine. For more information, speak with your doctor or pharmacist.
Elderly people may be more vulnerable to this medication's side effects, including diarrhoea, swelling of the hands, feet, ankles, or ankles, sudden/unexplained weight gain, unusual fatigue, shortness of breath, and QT prolongation (see above).
Women who are or may become pregnant should not handle this medication or breathe the dust from the pills since it can be absorbed through the skin and lungs and may harm an unborn child.
If you are pregnant or want to become pregnant, let your doctor know. A pregnancy test may be requested by your doctor prior to the start of this medication. Dasatinib usage should be avoided if trying to conceive. An unborn child could suffer from dasatinib. While taking this drug and for 30 days following the last dose, women of reproductive age should inquire about trustworthy methods of birth control. While using this medicine and for 30 days following the last dose, men should utilise effective birth control methods with female partners who are of reproductive age. Talk to your doctor soon away about the risks and advantages of this drug if you or your partner becomes pregnant.
It is unclear whether this medication enters breast milk. Breastfeeding is not advised while taking this medication and for two weeks after stopping treatment due to the potential harm to the baby. Before breastfeeding, speak with your doctor.
Side Effects of Dasatinib :
There may be symptoms including diarrhoea, vomiting, nausea, discomfort in the joints and muscles, and headaches. Inform your doctor or pharmacist as soon as possible if any of these side effects persist or get worse.
Serious side effects are possible for those taking this medicine. However, your doctor has recommended this medication to you because they believe that it will benefit you more than it will harm you. Your risk may be reduced by your doctor performing careful monitoring.
If you have any severe side effects, such as a dry cough, pain or swelling in your hands, feet, ankles, or ankles, rapid or unexplained weight gain, or shortness of breath, call your doctor straight once.
If you have any extremely significant side effects, such as vomit that resembles coffee grounds, black or bloody faeces, severe dizziness, fainting, a fast, slow, or irregular heartbeat, chest discomfort, confusion, or weakness on one side of the body, seek medical attention right once.
Dasatinib can occasionally cause negative effects since it quickly kills cancer cells (tumor lysis syndrome). Your doctor may prescribe an additional medication and advise you to drink plenty of fluids to reduce your risk. Inform your doctor right once if you experience any of the following symptoms: muscle spasms or weakness, low back/side pain (flank pain), kidney-related symptoms (painful urination, pink or bloody urine, change in the volume of urine).
Due to the medication's decreased bone marrow function, there may be fewer red, white, and platelet blood cells in the body. This effect can result in anaemia, weaken your body's defences against infection, or make you more prone to bleeding and bruising. If you experience any of the following symptoms, contact your doctor straight away: unusual fatigue, pale complexion, signs of infection (such as a persistent sore throat, a fever, chills), and easy bleeding or bruising.
Rarely will this medication cause a very serious allergic reaction. However, if you experience any major adverse reaction symptoms, such as a rash, itching or swelling (particularly of the face, tongue, or throat), severe dizziness, or difficulty breathing, seek medical attention right away.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Drug Interactions of Dasatinib :
Drug interactions could alter how your medications function or raise the possibility of major negative side effects. All probable medication interactions are not included in this document. Keep a list of everything you use, including herbal products, prescription and over-the-counter medications, and provide it to your doctor and pharmacist. Without your doctor's approval, never start, stop, or change the dosage of any medications.
Other medications that can cause bleeding or bruising, such as antiplatelet medications like clopidogrel, NSAIDs like ibuprofen/naproxen, "blood thinners" like warfarin/dabigatran, and medications that lower stomach acid, such as antacids, H2 blockers like famotidine/ranitidine, and proton pump inhibitors like omeprazole, are some products that may interact with this medication.
When used with this drug, aspirin can raise the risk of bleeding. But if your doctor has advised you to take low-dose aspirin (about 81–162 milligrammes a day) to prevent heart attacks or strokes, you should keep doing so unless your doctor gives you another order. For more information, speak to your doctor or pharmacist.
Dasatinib's ability to function may be impacted by the way other drugs interact with the clearance of dasatinib from your body. Examples include rifamycins (such as rifampin, rifabutin), azole antifungals (such as itraconazole, ketoconazole), dexamethasone, macrolide antibiotics (such as clarithromycin), saquinavir, St. John's wort, and telithromycin, among others.
Missed dose of Dasatinib :
If you miss a dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Over dose of Dasatinib :
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call a poison control center right away.
Storage of Dasatinib :
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Other Information of Dasatinib :
DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children.
Cost of Dasatinib :
The lowest MyGenericPharmacy.com price for the most common version of Sprycel (Dasatinib) is around $4.80, 83% off the average online retailing price of $1708.80.
MISSPELLINGS OF DASATINIB :
Sprycell, Sprycels, Spricel, Sprycil, Spryceel, Sprycal, Sprycelx, Sprycelz, Sprycelle, Sprycelk, Spreycel, Sprycellz, Spryceel, Sprycelp, Dasatinibb, Dasatinibe, Dasatinibx, Dasatinibb, Dasatnib, Dasatinibb, Dasatinibe, Dasatnib, Dasatinibz, Dasatnibe, Dasatinibc, Dasatinibee, Dasatinibv, Dasatninb, Dasatinbi.
Generic Sprycel™®: Dasatinib
Dasatinib is the chemical name of the active ingredient in Sprycel™®
Generic Buy Sprycel™ 20 mg (60 Pills) for Cancer
Buy online Generic Sprycel™ 20 mg (60 Pills), Sprycel Cost, Price $288.00 at 83% Discount.
Other name brands for this medication
Phyrago, Nextki, Beedan, Alsatinib, Leu Kinib, Dasapan, Dasamaps, Dasamyl, Dasanat, Dsatinib ML
Possible Uses of Dasatinib :
Certain forms of cancer are treated with this drug (chronic myeloid leukemia-CML, acute lymphoblastic leukemia-ALL). It inhibits or stops the development of cancer cells.
Before using Dasatinib :
Before taking dasatinib, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as lactose), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
How to take Dasatinib :
Before beginning to take dasatinib and each time you receive a refill, read the Patient Information Leaflet if it is available from your pharmacist. Ask your physician or pharmacist if you have any queries.
Take this medication by mouth once daily, generally with or without meal, as prescribed by your doctor. Completely swallow the tablets. The tablets must not be chewed, crushed, or broken.
The dosage is determined by your medical history, treatment response, lab results, and any additional medications you may be taking. The dosage for kids is also determined by weight. Inform your physician and pharmacist of all the products you consume (including prescription drugs, nonprescription drugs, and herbal products).
Usage this medication just as directed and never up the dosage, frequency, or duration of use. Your disease won't get better any faster, and you'll be at a higher risk for negative side effects.
Avoid ingesting antacids within two hours of taking this medication or immediately afterward since they will hinder your body from fully absorbing it. Examples of such antacids include aluminum/magnesium hydroxide and calcium carbonate.
If you're taking this medication, avoid eating or drinking grapefruit unless your doctor or pharmacist advises it's safe for you to. The likelihood of this medication's negative effects can be increased by grapefruit. For more information, speak to your doctor or pharmacist.
Women who are or may become pregnant should not handle this medication or breathe the dust from the pills since it can be absorbed through the skin and lungs and may harm an unborn child.
Precautions When Using Dasatinib :
Inform your doctor or pharmacist about your medical history before using this drug, especially of: bleeding issues, an ongoing or recent infection, heart issues (such as an irregular heartbeat), and liver issues (such as hepatitis B).
A disorder that alters the heart rhythm could be brought on by dasatinib (QT prolongation). Rarely, QT prolongation can result in fast/irregular heartbeat that is significant (rarely fatal) and other symptoms including acute dizziness and fainting that require immediate medical intervention.
If you take other medications or have certain medical problems that could raise your risk of QT prolongation, you should consult your doctor. Before taking dasatinib, inform your doctor or pharmacist of all the medications you take and any medical conditions you may have, such as certain heart conditions (heart failure, a slow heartbeat, an EKG finding called QT prolongation), a family history of certain heart conditions, and any of the following (QT prolongation in the EKG, sudden cardiac death).
Your risk of QT prolongation may also increase if your blood contains too little potassium or magnesium. This risk could rise if you take specific medications (such diuretics or "water pills") or experience symptoms like excessive sweating, diarrhoea, or vomiting. Ask your doctor for advice on how to use dasatinib safely.
Dasatinib may increase your risk of infection or exacerbate any existing infections. Stay away from persons who may be infected and infect others (such as chickenpox, measles, flu). If you have been exposed to an infection or would need additional information, speak with your doctor.
Before receiving any immunisations or vaccinations, let your doctor know that you are taking dasatinib. Avoid interacting with anyone who has just received a live vaccine (such as flu vaccine inhaled through the nose).
Avoid engaging in activities like contact sports and exercise caution while handling razors and other sharp devices, such as nail cutters.
The development and growth of a child's bones may be impacted by this medicine. For more information, speak with your doctor or pharmacist.
Elderly people may be more vulnerable to this medication's side effects, including diarrhoea, swelling of the hands, feet, ankles, or ankles, sudden/unexplained weight gain, unusual fatigue, shortness of breath, and QT prolongation (see above).
Women who are or may become pregnant should not handle this medication or breathe the dust from the pills since it can be absorbed through the skin and lungs and may harm an unborn child.
If you are pregnant or want to become pregnant, let your doctor know. A pregnancy test may be requested by your doctor prior to the start of this medication. Dasatinib usage should be avoided if trying to conceive. An unborn child could suffer from dasatinib. While taking this drug and for 30 days following the last dose, women of reproductive age should inquire about trustworthy methods of birth control. While using this medicine and for 30 days following the last dose, men should utilise effective birth control methods with female partners who are of reproductive age. Talk to your doctor soon away about the risks and advantages of this drug if you or your partner becomes pregnant.
It is unclear whether this medication enters breast milk. Breastfeeding is not advised while taking this medication and for two weeks after stopping treatment due to the potential harm to the baby. Before breastfeeding, speak with your doctor.
Side Effects of Dasatinib :
There may be symptoms including diarrhoea, vomiting, nausea, discomfort in the joints and muscles, and headaches. Inform your doctor or pharmacist as soon as possible if any of these side effects persist or get worse.
Serious side effects are possible for those taking this medicine. However, your doctor has recommended this medication to you because they believe that it will benefit you more than it will harm you. Your risk may be reduced by your doctor performing careful monitoring.
If you have any severe side effects, such as a dry cough, pain or swelling in your hands, feet, ankles, or ankles, rapid or unexplained weight gain, or shortness of breath, call your doctor straight once.
If you have any extremely significant side effects, such as vomit that resembles coffee grounds, black or bloody faeces, severe dizziness, fainting, a fast, slow, or irregular heartbeat, chest discomfort, confusion, or weakness on one side of the body, seek medical attention right once.
Dasatinib can occasionally cause negative effects since it quickly kills cancer cells (tumor lysis syndrome). Your doctor may prescribe an additional medication and advise you to drink plenty of fluids to reduce your risk. Inform your doctor right once if you experience any of the following symptoms: muscle spasms or weakness, low back/side pain (flank pain), kidney-related symptoms (painful urination, pink or bloody urine, change in the volume of urine).
Due to the medication's decreased bone marrow function, there may be fewer red, white, and platelet blood cells in the body. This effect can result in anaemia, weaken your body's defences against infection, or make you more prone to bleeding and bruising. If you experience any of the following symptoms, contact your doctor straight away: unusual fatigue, pale complexion, signs of infection (such as a persistent sore throat, a fever, chills), and easy bleeding or bruising.
Rarely will this medication cause a very serious allergic reaction. However, if you experience any major adverse reaction symptoms, such as a rash, itching or swelling (particularly of the face, tongue, or throat), severe dizziness, or difficulty breathing, seek medical attention right away.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Drug Interactions of Dasatinib :
Drug interactions could alter how your medications function or raise the possibility of major negative side effects. All probable medication interactions are not included in this document. Keep a list of everything you use, including herbal products, prescription and over-the-counter medications, and provide it to your doctor and pharmacist. Without your doctor's approval, never start, stop, or change the dosage of any medications.
Other medications that can cause bleeding or bruising, such as antiplatelet medications like clopidogrel, NSAIDs like ibuprofen/naproxen, "blood thinners" like warfarin/dabigatran, and medications that lower stomach acid, such as antacids, H2 blockers like famotidine/ranitidine, and proton pump inhibitors like omeprazole, are some products that may interact with this medication.
When used with this drug, aspirin can raise the risk of bleeding. But if your doctor has advised you to take low-dose aspirin (about 81–162 milligrammes a day) to prevent heart attacks or strokes, you should keep doing so unless your doctor gives you another order. For more information, speak to your doctor or pharmacist.
Dasatinib's ability to function may be impacted by the way other drugs interact with the clearance of dasatinib from your body. Examples include rifamycins (such as rifampin, rifabutin), azole antifungals (such as itraconazole, ketoconazole), dexamethasone, macrolide antibiotics (such as clarithromycin), saquinavir, St. John's wort, and telithromycin, among others.
Missed dose of Dasatinib :
If you miss a dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Over dose of Dasatinib :
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call a poison control center right away.
Storage of Dasatinib :
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Other Information of Dasatinib :
DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children.
Cost of Dasatinib :
The lowest MyGenericPharmacy.com price for the most common version of Sprycel (Dasatinib) is around $4.80, 83% off the average online retailing price of $1708.80.
MISSPELLINGS OF DASATINIB :
Sprycell, Sprycels, Spricel, Sprycil, Spryceel, Sprycal, Sprycelx, Sprycelz, Sprycelle, Sprycelk, Spreycel, Sprycellz, Spryceel, Sprycelp, Dasatinibb, Dasatinibe, Dasatinibx, Dasatinibb, Dasatnib, Dasatinibb, Dasatinibe, Dasatnib, Dasatinibz, Dasatnibe, Dasatinibc, Dasatinibee, Dasatinibv, Dasatninb, Dasatinbi.
FAQ
1. What is Dasatinib and its use?
Dasatinib is a medical drug that belongs to a class of medication called Kinase inhibitors. A medicine used to treat specific kinds of chronic myeloid leukaemia or acute lymphoblastic leukaemia that are positive for the Philadelphia chromosome in adults and kids aged one year and older. It is also being investigated for the treatment of further cancers.
2. What are the side effects of using dasatinib?
Pleural effusion and fluid retention are possible side effects of dasatinib (fluid build-up around your lungs). If you experience a decrease in urine output, noisy or rattling breathing, problems breathing, swelling in the fingers, hands, feet, or lower legs, weight gain, or any of these symptoms, consult your doctor straight once.
3. How long can I take dasatinib?
In clinical trials, Sprycel was administered for five years as a long-term therapy. Typically, you continue taking it as long as your tests indicate it is functioning well. Your health hasn't gotten worse.
4. Which is better, imatinib or dasatinib?
Intention-to-treat analysis revealed that the dasatinib group's 4-year event-free survival rate (71.0%; 95% CI, 56.2%-89.6%) was substantially higher than the imatinib group's (48.9%; 95% CI, 32.0%-74.5%), according to the log-rank test.
5. How effective is dasatinib?
Responses brought on by dasatinib were persistent. PFS was 75% and 94%, respectively, after 24 months in imatinib-resistant and -intolerant patients. OS at 24 months was 94%, with 100% of those who were imatinib-intolerant and 92% of those who were imatinib-resistant surviving.
6. Does dasatinib cause weight gain?
Fluid retention from dasatinib, including pleural effusion, is possible (fluid build-up around your lungs). Consult your doctor right away if you experience any of the following symptoms: a reduction in urine output, noisy or rattling breathing, difficulties breathing, swelling in the fingers, hands, feet, or lower legs, difficulty breathing, or weight gain.
7. Does dasatinib cause depression?
Depression (all degrees) occurred in 6.8% of patients in a trial of adjuvant imatinib for GIST patients, while grade 3/4 depression occurred in 0.9% of patients. Depression is described as affecting 1% to more than 10% of individuals in the dasatinib prescribing material; the depression grade is not mentioned.
8. Does dasatinib cause infertility?
Although dasatinib-treated female mice had higher embryonic resorption, lower implantation, and fewer viable embryos, second- or third-generation TKIs were found to have negligible effects on fertility in preclinical trials.
9. How long does sprycel take to work?
Shortly after you start taking Sprycel, it starts to work. Within one to two months, the medicine may start to work on your body. Some Sprycel users experienced a full recovery (no sign of cancer cells in two bone marrow tests). In trials, this outcome was shown after roughly three months of therapy.
