Generic Stivarga™®: Regorafenib
Regorafenib is the chemical name of the active ingredient in Stivarga™®
Generic Buy Stivarga™ 40 mg (28 Pills) for Cancer
Buy online Generic Stivarga™ 40 mg (28 Pills), Stivarga Cost, Price $659.40 at 51% Discount.
Other name brands for this medication
Nublexa, Regonat
Possible Uses of Regorafenib :
The drug rogorafenib is used to treat rectum and colon cancer. Moreover, it is utilised to treat digestive system cancer as well as liver cancer (gastrointestinal stromal tumor). It inhibits or stops the development of cancer cells.
Before using Regorafenib :
Before taking regorafenib, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
How to take Regorafenib :
Before beginning to use regorafenib and each time you receive a refill, read the Patient Information Leaflet from your pharmacist if one is available. Ask your physician or pharmacist if you have any queries.
When prescribed by your doctor, take this medication orally with a low-fat meal once day for 21 days, followed by a 7-day break from the prescription. One treatment cycle has concluded. As your doctor has instructed, carry on taking the medication in this manner. Completely ingest the medication. The tablets must not be chewed, split, or crushed.
Your medical condition and treatment response will determine the dosage. Use this medication just as directed and never up the dosage, frequency, or duration of usage. Your disease won't get better any faster, and you'll be at a higher risk for negative side effects.
To reap the greatest benefits from this drug, take it frequently. Every day that you are supposed to take it, don't forget to do so at the same time.
If you're taking this medication, avoid eating or drinking grapefruit unless your doctor or pharmacist advises it's safe for you to. The likelihood of this medication's negative effects can be increased by grapefruit. For more information, speak to your doctor or pharmacist.
Women who are or may become pregnant should not handle this medication or breathe the dust from the pills since it can be absorbed through the skin and lungs and may harm an unborn child.
Precautions When Using Regorafenib :
Tell your doctor or pharmacist about all of your medical history before taking this medication, especially of any liver issues, high blood pressure, heart disease (including heart attacks and chest pain), bleeding issues (such as bleeding of the stomach or intestines), blood vessel issues (such as an aneurysm or a tear or break in the aorta or other blood vessels), and recent major surgery or injury.
Inform your surgeon or dentist of all the products you use prior to surgery (including prescription drugs, nonprescription drugs, and herbal products). You could be instructed to stop taking regorafenib at least two weeks before to surgery by your physician or dentist. Wound healing may be slowed down by this medicine. Observe all directions regarding when to restart or stop using this medication.
Before to receiving any immunisations or vaccinations, let your healthcare provider know if you are on regorafenib. Avoid interacting with anyone who has just received a live vaccine (such as flu vaccine inhaled through the nose).
Avoid engaging in activities like contact sports and exercise caution while handling razors and other sharp devices, such as nail cutters.
By taking this medication, older persons may have a higher risk of developing high blood pressure.
If you are pregnant or want to become pregnant, let your doctor know. Regorafenib usage should not be accompanied by pregnancy. Regorafenib might be harmful to an unborn child. While using this drug and for two months after discontinuing therapy, both women and men should inquire about effective birth control methods. Talk to your doctor soon away about the risks and advantages of this drug if you or your partner becomes pregnant.
Women who are or may become pregnant should not handle this medication or breathe the dust from the pills since it can be absorbed through the skin and lungs and may harm an unborn child.
If this drug enters breast milk is unknown. Breastfeeding is not advised while taking this medication and for two weeks after stopping treatment due to the potential harm to the baby. Before breastfeeding, speak with your doctor.
Side Effects of Regorafenib :
It's possible to experience diarrhoea, pain or soreness in the mouth or throat, flavour changes, dry mouth, appetite loss, hair loss, voice changes, weight loss, or muscular stiffness. Inform your doctor or pharmacist as soon as possible if any of these side effects persist or get worse.
Serious side effects are possible for those taking this medicine. But, your doctor has recommended this medication to you because they believe that it will benefit you more than it will harm you. Your risk may be reduced by your doctor performing careful monitoring.
A skin reaction known as the hand-foot skin reaction may occasionally develop on your hands or feet as a result of treatment with this medication (palmar-plantar erythrodysesthesia). Asian Americans are more vulnerable. If your hands or feet start to swell, hurt, turn red, peel, blister, or feel tingly or burning, call your doctor immediately away. Heat or pressure on your hands or feet might exacerbate the discomfort. Avoid spending too much time in the sun, tanning beds, and sunlamps, as well as overheating (for example, hot dishwater, long hot baths). When outside, wear protective gear and sunscreen. Avoid applying pressure to the knees, feet, or elbows (such as leaning on elbows, kneeling, taking long walks). Put on comfy shoes and loose clothing. Your doctor may prescribe an additional drug to address the symptoms of your hand-foot reaction, stop or postpone your regorafenib treatment, or both, depending on how severe they are.
Your blood pressure may increase if you take this medication. Regularly check your blood pressure, and let your doctor know if the readings are excessive. Your doctor might prescribe medication to lower your blood pressure.
Inform your doctor right away if you experience any severe side effects, such as sluggish wound healing, dehydration symptoms (such as extreme thirst, lightheadedness, decreased urination), mineral imbalance symptoms (such as muscle cramps/weakness, irregular heartbeat, mental/mood changes), infection symptoms (such as persistent sore throat, fever, chills), or thyroid underactivity symptoms (weight gain, cold intolerance, unusual tiredness, slow heartbeat).
Serious bleeding problems may result from this drug. If you experience any serious bleeding symptoms, such as easy bleeding or bruising, excruciating stomach/abdominal pain, bloody or coffee-ground-looking vomit, black or tarry stools, unusual vaginal bleeding, pink or red urine, or coughing up blood, call your doctor straight once.
If you have any extremely significant side effects, such as: heart attack symptoms (such as pain in the jaw, left arm, or chest), a seizure, a severe headache, confusion, sudden vision changes, weakness on one side of the body, or difficulty speaking, get immediate medical attention.
Rarely will this medication cause a very serious allergic reaction. But, if you experience any major adverse reaction symptoms, such as a rash, itching or swelling (particularly of the face, tongue, or throat), severe dizziness, or difficulty breathing, seek medical attention right away.
Regorafenib frequently results in a minor rash, which is typically not dangerous. You might not be able to distinguish it from a rare rash that might indicate a severe allergic reaction, though. Immediately seek medical attention if you experience any rash.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Drug Interactions of Regorafenib :
Medication interactions could alter how your medications function or raise the possibility of major negative side effects. All probable medication interactions are not included in this document. Maintain a list of everything you use, including herbal products, prescription and over-the-counter medications, and provide it to your doctor and pharmacist. Without your doctor's approval, never start, stop, or change the dosage of any medications.
Irinotecan and other medications that can cause bleeding or bruising are among products that may interact with this medication (including antiplatelet drugs such as clopidogrel, NSAIDs such as ibuprofen, "blood thinners" such as warfarin).
When used with this drug, aspirin can raise the risk of bleeding. However if your doctor has advised you to take low-dose aspirin (about 81–162 milligrammes a day) to prevent heart attacks or strokes, you should keep doing so unless your doctor gives you another order. For more information, speak to your doctor or pharmacist.
Regorafenib's ability to be eliminated from your body can be impacted by other medications, which could change how well it functions. Nefazodone, ritonavir, St. John's wort, telithromycin, azole antifungals like ketoconazole and itraconazole, macrolide antibiotics like clarithromycin, HIV protease inhibitors like nelfinavir, rifamycins like rifabutin and rifampin, and medications for treating seizures like phenytoin are a few examples.
Missed dose of Regorafenib :
If you miss a dose and remember on the same day, take it as soon as you remember. If you remember on the next day, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Over dose of Regorafenib :
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call a poison control center right away.
Storage of Regorafenib :
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Other Information of Regorafenib :
DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children.
Cost of Regorafenib :
The lowest MyGenericPharmacy.com price for the most common version of Stivarga (Regorafenib) is around $23.55, 51% off the average online retailing price of $999.00.
MISSPELLINGS OF REGORAFENIB :
Stivargaa, Stivarg, Stivargaax, Stivargaa, Stivarge, Stivargga, Stivargaa, Stivaraga, Stivargz, Stivargad, Stivargae, Stivargaex, Stivargga, Stivarga, Regorafenibb, Regorafenibe, Regorafenibx, Regorafenibz, Regorafeniba, Regorafenibb, Regorafenibbe, Regorafenibee, Regorafnib, Regorafenibc, Regorafenibd, Regorafenibe, Regorafnibb, Regorafebin, Regorafnibx.
Generic Stivarga™®: Regorafenib
Regorafenib is the chemical name of the active ingredient in Stivarga™®
Generic Buy Stivarga™ 40 mg (28 Pills) for Cancer
Buy online Generic Stivarga™ 40 mg (28 Pills), Stivarga Cost, Price $659.40 at 51% Discount.
Other name brands for this medication
Nublexa, Regonat
Possible Uses of Regorafenib :
The drug rogorafenib is used to treat rectum and colon cancer. Moreover, it is utilised to treat digestive system cancer as well as liver cancer (gastrointestinal stromal tumor). It inhibits or stops the development of cancer cells.
Before using Regorafenib :
Before taking regorafenib, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
How to take Regorafenib :
Before beginning to use regorafenib and each time you receive a refill, read the Patient Information Leaflet from your pharmacist if one is available. Ask your physician or pharmacist if you have any queries.
When prescribed by your doctor, take this medication orally with a low-fat meal once day for 21 days, followed by a 7-day break from the prescription. One treatment cycle has concluded. As your doctor has instructed, carry on taking the medication in this manner. Completely ingest the medication. The tablets must not be chewed, split, or crushed.
Your medical condition and treatment response will determine the dosage. Use this medication just as directed and never up the dosage, frequency, or duration of usage. Your disease won't get better any faster, and you'll be at a higher risk for negative side effects.
To reap the greatest benefits from this drug, take it frequently. Every day that you are supposed to take it, don't forget to do so at the same time.
If you're taking this medication, avoid eating or drinking grapefruit unless your doctor or pharmacist advises it's safe for you to. The likelihood of this medication's negative effects can be increased by grapefruit. For more information, speak to your doctor or pharmacist.
Women who are or may become pregnant should not handle this medication or breathe the dust from the pills since it can be absorbed through the skin and lungs and may harm an unborn child.
Precautions When Using Regorafenib :
Tell your doctor or pharmacist about all of your medical history before taking this medication, especially of any liver issues, high blood pressure, heart disease (including heart attacks and chest pain), bleeding issues (such as bleeding of the stomach or intestines), blood vessel issues (such as an aneurysm or a tear or break in the aorta or other blood vessels), and recent major surgery or injury.
Inform your surgeon or dentist of all the products you use prior to surgery (including prescription drugs, nonprescription drugs, and herbal products). You could be instructed to stop taking regorafenib at least two weeks before to surgery by your physician or dentist. Wound healing may be slowed down by this medicine. Observe all directions regarding when to restart or stop using this medication.
Before to receiving any immunisations or vaccinations, let your healthcare provider know if you are on regorafenib. Avoid interacting with anyone who has just received a live vaccine (such as flu vaccine inhaled through the nose).
Avoid engaging in activities like contact sports and exercise caution while handling razors and other sharp devices, such as nail cutters.
By taking this medication, older persons may have a higher risk of developing high blood pressure.
If you are pregnant or want to become pregnant, let your doctor know. Regorafenib usage should not be accompanied by pregnancy. Regorafenib might be harmful to an unborn child. While using this drug and for two months after discontinuing therapy, both women and men should inquire about effective birth control methods. Talk to your doctor soon away about the risks and advantages of this drug if you or your partner becomes pregnant.
Women who are or may become pregnant should not handle this medication or breathe the dust from the pills since it can be absorbed through the skin and lungs and may harm an unborn child.
If this drug enters breast milk is unknown. Breastfeeding is not advised while taking this medication and for two weeks after stopping treatment due to the potential harm to the baby. Before breastfeeding, speak with your doctor.
Side Effects of Regorafenib :
It's possible to experience diarrhoea, pain or soreness in the mouth or throat, flavour changes, dry mouth, appetite loss, hair loss, voice changes, weight loss, or muscular stiffness. Inform your doctor or pharmacist as soon as possible if any of these side effects persist or get worse.
Serious side effects are possible for those taking this medicine. But, your doctor has recommended this medication to you because they believe that it will benefit you more than it will harm you. Your risk may be reduced by your doctor performing careful monitoring.
A skin reaction known as the hand-foot skin reaction may occasionally develop on your hands or feet as a result of treatment with this medication (palmar-plantar erythrodysesthesia). Asian Americans are more vulnerable. If your hands or feet start to swell, hurt, turn red, peel, blister, or feel tingly or burning, call your doctor immediately away. Heat or pressure on your hands or feet might exacerbate the discomfort. Avoid spending too much time in the sun, tanning beds, and sunlamps, as well as overheating (for example, hot dishwater, long hot baths). When outside, wear protective gear and sunscreen. Avoid applying pressure to the knees, feet, or elbows (such as leaning on elbows, kneeling, taking long walks). Put on comfy shoes and loose clothing. Your doctor may prescribe an additional drug to address the symptoms of your hand-foot reaction, stop or postpone your regorafenib treatment, or both, depending on how severe they are.
Your blood pressure may increase if you take this medication. Regularly check your blood pressure, and let your doctor know if the readings are excessive. Your doctor might prescribe medication to lower your blood pressure.
Inform your doctor right away if you experience any severe side effects, such as sluggish wound healing, dehydration symptoms (such as extreme thirst, lightheadedness, decreased urination), mineral imbalance symptoms (such as muscle cramps/weakness, irregular heartbeat, mental/mood changes), infection symptoms (such as persistent sore throat, fever, chills), or thyroid underactivity symptoms (weight gain, cold intolerance, unusual tiredness, slow heartbeat).
Serious bleeding problems may result from this drug. If you experience any serious bleeding symptoms, such as easy bleeding or bruising, excruciating stomach/abdominal pain, bloody or coffee-ground-looking vomit, black or tarry stools, unusual vaginal bleeding, pink or red urine, or coughing up blood, call your doctor straight once.
If you have any extremely significant side effects, such as: heart attack symptoms (such as pain in the jaw, left arm, or chest), a seizure, a severe headache, confusion, sudden vision changes, weakness on one side of the body, or difficulty speaking, get immediate medical attention.
Rarely will this medication cause a very serious allergic reaction. But, if you experience any major adverse reaction symptoms, such as a rash, itching or swelling (particularly of the face, tongue, or throat), severe dizziness, or difficulty breathing, seek medical attention right away.
Regorafenib frequently results in a minor rash, which is typically not dangerous. You might not be able to distinguish it from a rare rash that might indicate a severe allergic reaction, though. Immediately seek medical attention if you experience any rash.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Drug Interactions of Regorafenib :
Medication interactions could alter how your medications function or raise the possibility of major negative side effects. All probable medication interactions are not included in this document. Maintain a list of everything you use, including herbal products, prescription and over-the-counter medications, and provide it to your doctor and pharmacist. Without your doctor's approval, never start, stop, or change the dosage of any medications.
Irinotecan and other medications that can cause bleeding or bruising are among products that may interact with this medication (including antiplatelet drugs such as clopidogrel, NSAIDs such as ibuprofen, "blood thinners" such as warfarin).
When used with this drug, aspirin can raise the risk of bleeding. However if your doctor has advised you to take low-dose aspirin (about 81–162 milligrammes a day) to prevent heart attacks or strokes, you should keep doing so unless your doctor gives you another order. For more information, speak to your doctor or pharmacist.
Regorafenib's ability to be eliminated from your body can be impacted by other medications, which could change how well it functions. Nefazodone, ritonavir, St. John's wort, telithromycin, azole antifungals like ketoconazole and itraconazole, macrolide antibiotics like clarithromycin, HIV protease inhibitors like nelfinavir, rifamycins like rifabutin and rifampin, and medications for treating seizures like phenytoin are a few examples.
Missed dose of Regorafenib :
If you miss a dose and remember on the same day, take it as soon as you remember. If you remember on the next day, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Over dose of Regorafenib :
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call a poison control center right away.
Storage of Regorafenib :
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Other Information of Regorafenib :
DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children.
Cost of Regorafenib :
The lowest MyGenericPharmacy.com price for the most common version of Stivarga (Regorafenib) is around $23.55, 51% off the average online retailing price of $999.00.
MISSPELLINGS OF REGORAFENIB :
Stivargaa, Stivarg, Stivargaax, Stivargaa, Stivarge, Stivargga, Stivargaa, Stivaraga, Stivargz, Stivargad, Stivargae, Stivargaex, Stivargga, Stivarga, Regorafenibb, Regorafenibe, Regorafenibx, Regorafenibz, Regorafeniba, Regorafenibb, Regorafenibbe, Regorafenibee, Regorafnib, Regorafenibc, Regorafenibd, Regorafenibe, Regorafnibb, Regorafebin, Regorafnibx.
FAQ
1. What is Regorafenib and its use?
Regorafenib is a medical drug that belongs to a class of medication called Kinase inhibitors. Metastatic carcinoma (cancer that has spread) of the colon and rectum is treated with regorafenib. It is administered to people who have previously received unsuccessful treatment for cancer with other drugs. Regorafenib stops cancers from spreading.
2. Is regorafenib a chemotherapy?
The chemotherapeutic medication Stivarga® is sold under the brand name regorafenib. In rare instances, medical practitioners may refer to the generic medicine name regorafenib by the brand name Stivarga®. Regorafenib is a targeted therapy and a type of drug.
3. How long is regorafenib therapy?
A 21-day period of regorafenib treatment will be followed by a 7-day period of rest during the course of the treatment, which will be administered in 28-day cycles. If there is toxicity, the dose may be lowered or the course of treatment may be stopped in accordance with the SPCs (SPC).
4. Does regorafenib cause hair loss?
You could experience hair loss or thinning. This usually starts two to three weeks following the start of the treatment. Any body hair, including pubic, underarm, legs/arms, eyelashes, and nose hair, may experience this hair loss. Using scarves, wigs, caps, and hairpieces could be beneficial.
5. When is the best time to take STIVARGA?
STIVARGA should be taken after a low-fat meal and should be swallowed whole with water. Less than 600 calories and less than 30% fat are found in this meal. You can select the time of day you want to take STIVARGA. You could opt to have it along with your breakfast, dinner, or lunch.
6. Does STIVARGA shrink tumors?
Regorafenib can inhibit the growth of some tumours and even cause them to shrink, however it is unclear if this would prolong life. Regorafenib frequently causes stomach discomfort, diarrhoea, fatigue or weakness, mouth or throat irritation, fever, appetite loss, and weight loss.
7. Can Stivarga cause blood clots?
Side effects of stivarga include brown or pink urine, Red or black (tar-like) faeces are common, blood or blood clots being coughed up, etc.
