Generic Tracleer™®: Bosentan
Bosentan is the chemical name of the active ingredient in Tracleer™®
Generic Buy Tracleer™ 62.5 mg for Blood Pressure
Buy online Generic Tracleer (tm) 62.5 mg (10 Pills), Tracleer Cost, Price $130.00 at 14% Discount.
Tablet Chemical Name: Bosentan.
Other name brands for this medication
Lupibose
Possible Uses of Bosentas: Bosentan is used to treat the symptoms of pulmonary arterial hypertension. This is the high blood pressure that occurs in the main artery that carries blood from the right side of the heart (the ventricle) to the lungs. When the smaller blood vessels in the lungs become more resistant to blood flow, the right ventricle must work harder to pump enough blood through the lungs. Bosentan works by blocking a hormone (a naturally occurring substance), that is found in the blood and lungs in large quantities of the people with pulmonary arterial hypertension. Bosentan helps by increasing the supply of blood to the lungs and reducing the workload of the heart.
Before using Bosentas: In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Appropriate studies have not been performed on the relationship of age to the effects of bosentan in the pediatric population. Safety and efficacy have not been established. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of bosentan in the elderly. However, elderly patients are more likely to have age-related heart, liver, or kidney problems, which may require caution in patients receiving bosentan.
Pregnant women have demonstrated positive evidence of fetal abnormalities. This drug should not be used in women who are or may become pregnant because the risk clearly outweighs any possible benefit. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
How to take Bosentas: Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Also, do not change the dose or stop using this medicine without checking first with your doctor. It is very important that you understand the requirements of the Tracleer® access program, and become familiar with the Tracleer® educational materials and Patient Medication Guide. Direct any questions to your doctor or pharmacist before starting bosentan therapy. You may take this medicine with or without food. The dose of this medicine will be different for different patients. Follow your doctor\'s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
Precautions When Using Bosentas: It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly and to check for unwanted effects. It is also important that your doctor does a blood test to check your liver function before you start bosentan and each month after that. Using this medicine while you are pregnant can cause very serious birth defects. Use two forms of effective birth control to keep from getting pregnant while you are using this medicine (even if the medicine is temporarily stopped), and for at least one month after you stop taking the medicine. The most effective forms of birth control are hormone birth control pills, patches, shots, vaginal rings, or implants, an IUD, or a vasectomy (for men). One of these forms of birth control should be combined with a condom, a diaphragm, or a cervical cap. If a woman has had a tubal ligation, she does not need to use a second form of birth control. If you think you have become pregnant while using this medicine, tell your doctor right away. You must have a negative pregnancy test before you will be allowed to take this medicine. You will also be required to have a pregnancy test every month during your treatment. If you miss a period while you are using this medicine, tell your doctor right away. Liver problems may occur while you are using this medicine. Stop using this medicine and check with your doctor right away if you are having more than one of these symptoms: dark urine, fever with or without chills, light colored stools, loss of appetite, nausea and vomiting, skin rash, stomach pain, unusual tiredness, or yellow eyes or skin. Bosentan may decrease the amount of sperm men make and affect their ability to have children. If you plan to have children, talk with your doctor before using this medicine. This medicine may cause fluid retention (edema) in some patients. Check with your doctor right away if you are gaining weight rapidly; have swelling in your hands, ankles, feet, or all over the body; or if you have trouble with breathing while you are using this medicine. Pulmonary edema may occur while using this medicine. Stop using this medicine and check with your doctor right away if you have chest pain; difficult, fast, noisy breathing, sometimes with wheezing; blue lips and fingernails; pale skin; increased sweating; coughing that sometimes produces a pink frothy sputum; or shortness of breath. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Side Effects of Bosentas: Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur:
More common
Blurred vision
confusion
dizziness
dark urine
faintness or lightheadedness when getting up from a lying or sitting position
fever with or without chills
light-colored stools
loss of appetite
nausea and vomiting
stomach pain
sudden sweating
unusual tiredness or weakness
yellow eyes or skin or
Swelling.
Drug Interactions of Bosentas: Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Cyclosporine
Glyburide
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Missed dose of Bosentas: If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Overdose of Bosentas: If overdose is suspected, contact a poison control center or emergency room immediately.
Storage of Bosentas: Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children.
Other Information of Bosentas: DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.
COST OF Bosentas : The lowest MyGenericPharmacy.com price for the most common version of Tracleer (Tracleer) is around $13.00, 14% off the average online retailing price of $477.90.
Generic Tracleer™®: Bosentan
Bosentan is the chemical name of the active ingredient in Tracleer™®
Generic Buy Tracleer™ 62.5 mg for Blood Pressure
Buy online Generic Tracleer (tm) 62.5 mg (10 Pills), Tracleer Cost, Price $130.00 at 14% Discount.
Tablet Chemical Name: Bosentan.
Other name brands for this medication
Lupibose
Possible Uses of Bosentas: Bosentan is used to treat the symptoms of pulmonary arterial hypertension. This is the high blood pressure that occurs in the main artery that carries blood from the right side of the heart (the ventricle) to the lungs. When the smaller blood vessels in the lungs become more resistant to blood flow, the right ventricle must work harder to pump enough blood through the lungs. Bosentan works by blocking a hormone (a naturally occurring substance), that is found in the blood and lungs in large quantities of the people with pulmonary arterial hypertension. Bosentan helps by increasing the supply of blood to the lungs and reducing the workload of the heart.
Before using Bosentas: In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Appropriate studies have not been performed on the relationship of age to the effects of bosentan in the pediatric population. Safety and efficacy have not been established. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of bosentan in the elderly. However, elderly patients are more likely to have age-related heart, liver, or kidney problems, which may require caution in patients receiving bosentan.
Pregnant women have demonstrated positive evidence of fetal abnormalities. This drug should not be used in women who are or may become pregnant because the risk clearly outweighs any possible benefit. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
How to take Bosentas: Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Also, do not change the dose or stop using this medicine without checking first with your doctor. It is very important that you understand the requirements of the Tracleer® access program, and become familiar with the Tracleer® educational materials and Patient Medication Guide. Direct any questions to your doctor or pharmacist before starting bosentan therapy. You may take this medicine with or without food. The dose of this medicine will be different for different patients. Follow your doctor\'s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
Precautions When Using Bosentas: It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly and to check for unwanted effects. It is also important that your doctor does a blood test to check your liver function before you start bosentan and each month after that. Using this medicine while you are pregnant can cause very serious birth defects. Use two forms of effective birth control to keep from getting pregnant while you are using this medicine (even if the medicine is temporarily stopped), and for at least one month after you stop taking the medicine. The most effective forms of birth control are hormone birth control pills, patches, shots, vaginal rings, or implants, an IUD, or a vasectomy (for men). One of these forms of birth control should be combined with a condom, a diaphragm, or a cervical cap. If a woman has had a tubal ligation, she does not need to use a second form of birth control. If you think you have become pregnant while using this medicine, tell your doctor right away. You must have a negative pregnancy test before you will be allowed to take this medicine. You will also be required to have a pregnancy test every month during your treatment. If you miss a period while you are using this medicine, tell your doctor right away. Liver problems may occur while you are using this medicine. Stop using this medicine and check with your doctor right away if you are having more than one of these symptoms: dark urine, fever with or without chills, light colored stools, loss of appetite, nausea and vomiting, skin rash, stomach pain, unusual tiredness, or yellow eyes or skin. Bosentan may decrease the amount of sperm men make and affect their ability to have children. If you plan to have children, talk with your doctor before using this medicine. This medicine may cause fluid retention (edema) in some patients. Check with your doctor right away if you are gaining weight rapidly; have swelling in your hands, ankles, feet, or all over the body; or if you have trouble with breathing while you are using this medicine. Pulmonary edema may occur while using this medicine. Stop using this medicine and check with your doctor right away if you have chest pain; difficult, fast, noisy breathing, sometimes with wheezing; blue lips and fingernails; pale skin; increased sweating; coughing that sometimes produces a pink frothy sputum; or shortness of breath. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Side Effects of Bosentas: Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur:
More common
Blurred vision
confusion
dizziness
dark urine
faintness or lightheadedness when getting up from a lying or sitting position
fever with or without chills
light-colored stools
loss of appetite
nausea and vomiting
stomach pain
sudden sweating
unusual tiredness or weakness
yellow eyes or skin or
Swelling.
Drug Interactions of Bosentas: Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Cyclosporine
Glyburide
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Missed dose of Bosentas: If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Overdose of Bosentas: If overdose is suspected, contact a poison control center or emergency room immediately.
Storage of Bosentas: Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children.
Other Information of Bosentas: DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.
COST OF Bosentas : The lowest MyGenericPharmacy.com price for the most common version of Tracleer (Tracleer) is around $13.00, 14% off the average online retailing price of $477.90.
FAQ
1. What is Bosentas (Bosentan) and what is it used for?
Bosentan is a medical drug available to us under the brand name Bosentas that belongs to a class of medication called endothelin receptor antagonists. This medicine is generally used to treat high blood pressure in the blood vessels that carries blood from heart to the lungs by stopping a natural hormone called Endothelin that is responsible for narrowing of blood vessels.
2. When and how to use Bosentan?
Bosentan is available to us in a form of pill that must be taken by mouth with or without food as per your doctor's prescription. It is usually taken twice a day daily i.e. one at morning and other at evening. The dosage and length of the treatment is based on your medical condition, response to the treatment and other medicine that you may be taking for the same or different reason. Swallow the tablet whole rather than chewing or crushing it in your mouth as it may release all the drug in your mouth which increases the risk of side effects. Your doctor may start you with a low dose which will increase gradually. Take the medicine daily at the same time to get the most benefits from it. Do not increase your dose or take it more often than prescribed as this may also increase the risk of side effects without any improvement in your condition. Discuss all the other medicines that you might be taking along with Bosentan for the same or different reasons. Follow the medical prescription carefully and inform your doctor in case of any exception or confusion.
3. What are the side effects of Bosentan?
Common side effects observed while medicating with Bosentan are dizziness, flushing, joint pain or stuffy nose may occur. Inform your doctor if these conditions persist or get worse. There are some serious side effects which must be informed to the doctor right away if observed such as fast/pounding heartbeat, unusual tiredness, swelling ankles/feet, unusual/sudden weight gain, fainting, shortness of breath, coughing up blood, decrease in sperm production etc. There are also some severe allergic reactions involved with this medication which require immediate medical attention if observed such rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing etc.
4. Is Bosentan safe during pregnancy?
Bosentan is a kind of medical drug that has an ability to get absorbed through lungs as well as through skin. A pregnant woman must stay away from the drug and must not inhale or touch the drug as it can enter through and may harm an unborn baby. Contact the doctor if you touched or inhaled the drug during pregnancy.
5. Is Bosentan a safe medicine?
Bosentan is considered as a safe and effective medicine of class endothelin receptor antagonists in the treatment of adults with Pulmonary Arterial Hypertension. According to recent studies, administration of Bosentan for more than one year is generally comfortable. However in children, there is a lack of evidence.
6. How long does Bosentan take to work?
Bosentan is a kind of medicine that is generally started with a low dose and then increases gradually after some while so that risk of side effects is reduced and the body gets used to the medicine. Bosentan is not a cure but a controlling measure. It usually takes 1-2 months before you feel the full benefits from the medicine.
7. Is Bosentan an effective medicine?
According to a clinical study of Bosentan monotherapy, the survival rate of patients was 85.9 in the first year. The rate observes a reduction i.e. 73.4% in the second year. According to the WHO functional class, by the end of treatment, 25% of a total f 40 patients improved.
8. What precautions must be taken before using Bosentan?
Before starting the medication with Bosentan, one must inform the doctor regarding allergies related to this medicine, or any other allergies as these products may contain some ingredient that causes an allergic reaction inside your body. Tell your doctor if you have any medical history related to kidney disease, liver disease, anemia, etc. Inform your doctor regarding all the products you use including herbal, prescribed, and non-prescribed medicine before undergoing any surgery. Use of alcohol and marijuana will make you dizzier than its usual effect which must be avoided.
9. Which medicine interacts with Bosentan?
Interaction with a medicine generally refers to a change of effectiveness and potential risk that can develop in the body when two or more different drugs come into contact with one another inside the body. Medicines interacting with Bosentan include cyclosporine, HIV protease inhibitors, glyburide, ritonavir, paritaprevir, birth control pill, ring or patch, etc.
10. Can bosentan and warfarin be used together?
The medication of Bosentan with Warfarin may cause a decrease in anticoagulant properties of Warfarin. While both the medicine are used together, The (INR)International Normalized Ratio must be monitored more carefully and frequently bosentan is added or excluded while medicating with warfarin.
