Buy Generic Trexall (Methotrexate) Online

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About Generic Trexall® (Methotrexate)

Key Details

1. Generic Trexall™ 2.5mg for Skin care
2. Buy online Generic Trexall™ 2.5 mg (30 Pills), Trexall Cost, Price $12.00 at 76% Discount
3. Reduces joint pain and inflammation
4. Slows progression of rheumatoid arthritis
5. Improves skin plaques in psoriasis

How Generic Trexall Works

Generic Trexall (Methotrexate) works by blocking the activity of dihydrofolate reductase, an enzyme required for the production of DNA, RNA, and proteins. By limiting cell replication, it slows down the rapid growth of immune cells that drive inflammation in autoimmune diseases such as rheumatoid arthritis and psoriasis.

It also has immunosuppressive effects, helping reduce overactive immune responses that cause chronic inflammation and joint damage. In cancer treatment, it targets rapidly dividing cancer cells to weaken or stop tumor growth.

Drug Info

METHOTREXATE– ORAL (meth-o-TREX-ate)
Common Brand Name(s): Trexall™

Other name brands for this medication
Rasuvo, Rheumatrex, Folitrax, Mexate, Biotrexate, Oncotrex, Imutrex, Merex, Methocel, Remtrex

Uses of Trexall

This medicine is an antimetabolite used to treat psoriasis or rheumatoid arthritis. It may also be used to treat other conditions as determined by your doctor.

Before Using Trexall

WARNING: Serious, sometimes fatal, side effects have occurred in those using methotrexate. Therefore, this medicine should be used only to treat life-threatening cancer or severe cases of psoriasis or rheumatoid arthritis. Methotrexate has caused birth defects and fetal death. It is not recommended for use in women of child-bearing age unless no alternatives exist. Pregnant women who have psoriasis or rheumatoid arthritis must not use methotrexate. If you have kidney problems or excess body water ( ascites, pleural effusion), you must be closely monitored and your dose may be adjusted or stopped. Methotrexate ( usually at high dosages) has caused severe, even fatal, bone marrow suppression ( e.g., bone marrow makes cells that fight infections) and intestinal or stomach disease ( e.g., bleeding) when used at the same time as non-steroidal anti- inflammatory drugs ( NSAIDs) ( e.g., ibuprofen, naproxen). This drug may also cause liver problems when it is used for long periods of time. If you are using methotrexate long-term, liver biopsies should be performed. Methotrexate use has resulted in serious, possibly fatal, lung problems, skin reactions, diarrhea and mouth sores ( ulcerative stomatitis). Lumps ( tumors/abnormal growths) may appear during methotrexate use. The drug must be stopped and treatment may be needed. Consult your doctor immediately if new lumps/growths occur. When used to treat tumors, methotrexate sometimes causes 'tumor lysis syndrome' due to cell destruction. Promptly report symptoms ( e.g., irregular heartbeat, muscle weakness) if they occur. If you develop any of the following side effects, contact your doctor immediately: nausea, stomach pain, yellowing eyes or skin, dark urine, fever, fatigue, persistent sore throat, easy bruising or bleeding, black stools, change in amount of urine, skin rash, breathing problems, dry cough, diarrhea, or mouth sores. Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking corticosteroids, digoxin, etretinate, nonsteroidal anti-inflammatory drugs ( NSAIDs), probenecid, penicillin and sulfa antibiotics, trimethoprim, warfarin, or medicine for seizures. Inform your doctor of any other medical conditions, allergies, pregnancy, or breast-feeding. USE OF THIS MEDICINE IS NOT RECOMMENDED if you have a history of immune system disorders. Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine.

How to Use Trexall

Follow the directions for using this medicine provided by your doctor. Ask your doctor, nurse, or pharmacist any questions you have about this medicine. IF NAUSEA, VOMITING, OR LOSS OF APPETITE OCCUR, ask your doctor, nurse, or pharmacist for ways to lessen these effects.

Side Effects of Trexall

SIDE EFFECTS, that may go away during treatment, include nausea, loss of appetite, skin rash, or dizziness. If they continue or are bothersome, check with your doctor. CHECK WITH YOUR DOCTOR AS SOON AS POSSIBLE if you experience diarrhea; vomiting; abdominal pain; black tarry stools; unusual bruising or bleeding; sores on the mouth or lips; unusual tiredness or weakness; yellowing of the skin or eyes; darkened or bloody urine; joint pain; swelling of the feet or legs; fever or chills; dry cough; cough with congestion; shortness of breath or other breathing problems; or sore throat. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.

Precautions

KEEP ALL DOCTOR AND LABORATORY APPOINTMENTS while you are using this medicine. THIS MEDICINE MAY CAUSE increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to this medicine. Use a sunscreen or protective clothing if you must be outside for a prolonged period. THIS MEDICINE MAY REDUCE THE NUMBER OF BLOOD CELLS WHICH ARE NEEDED FOR CLOTTING. To prevent bleeding, avoid situations where bruising or injury may occur. THIS MEDICINE MAY LOWER YOUR RESISTANCE to infection. To prevent infection, avoid contact with people who have colds or other infections. Do not touch your eyes or the inside of your nose unless you have thoroughly washed your hands first. DO NOT DRINK ALCOHOL while you are taking this medicine. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. This includes any medicines that contain ibuprofen, naproxen, aspirin, salicylates, or any other medicine used to treat pain, fever, swelling, or arthritis. FOR BOTH MEN AND WOMEN, use an effective form of birth control during therapy and for up to 3 months after this medicine is stopped. DO NOT USE THIS MEDICINE if you are pregnant. IF YOU SUSPECT THAT YOU COULD BE PREGNANT, contact your doctor immediately. THIS MEDICINE IS EXCRETED IN BREAST MILK. DO NOT BREAST-FEED while taking this medicine.

Drug Interactions

Drug interactions can result in unwanted side effects or prevent a medicine from doing its job.Inform your doctor about all the medicines you take with and without a prescription.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Overdose

If overdose is suspected, contact a poison control center or emergency room immediately.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Cost of Trexall

The lowest MyGenericPharmacy.com price for the most common version of Trexall (Methotrexate) is around $0.40, 76% off the average online retailing price of $50.10.

What is Trexall / Methotrexate?
Trexall (Methotrexate) is a disease-modifying drug (DMARD) used to treat autoimmune diseases like rheumatoid arthritis and psoriasis, and also certain cancers. It decreases inflammation by suppressing overactive immune cells.

How Does Trexall Work?
It inhibits the enzyme dihydrofolate reductase, reducing the production of DNA and slowing rapid cell growth. This suppresses abnormal immune activity, reduces inflammation, and controls disease progression.

Benefits of Trexall

1. Reduces joint pain and inflammation
2. Slows progression of rheumatoid arthritis
3. Improves skin plaques in psoriasis
4. Prevents long-term joint damage
5. Helps control psoriatic arthritis
6. Effective low-dose immunosuppressant
7. Used in several cancers to slow cell growth

Dosage & How to Use

1. Take once weekly, never daily, unless specifically instructed by a doctor.
2. Usually taken orally with a full glass of water.
3. Dose varies based on condition:
4. Rheumatoid arthritis: typically 7.5–25 mg once weekly
5. Psoriasis: 10–25 mg once weekly
6. Cancer: doses are individualized and often higher
7. Folic acid supplements are often prescribed to reduce side effects.
8. Do not double doses if missed; contact your doctor for guidance.
9. Avoid alcohol to reduce liver strain.

Side Effects & Precautions
Common side effects may include:

1. Nausea, vomiting
2. Mouth sores
3. Fatigue
4. Hair thinning
5. Stomach upset
6. Increased sensitivity to sunlight

Precautions:

1. Regular liver, kidney, and blood tests required.
2. Avoid alcohol completely or keep minimum.
3. Do not use with NSAIDs unless approved by your doctor.
4. Avoid pregnancy; can harm unborn baby.
5. Avoid live vaccines.

Who Should Not Take Trexall

1. Pregnant or breastfeeding women
2. People with severe liver or kidney disease
3. Patients with immune deficiency or bone marrow disorders
4. Those with chronic alcoholism
5. Individuals with active infections
6. Anyone allergic to Methotrexate

Other Information of Trexall :
DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT out of the reach of children. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.

MISSPELLINGS OF TREXALL :
Trexal, Trexxall, Trixall, Trexell, Trexell, Trexaul, Trexawl, Trrexall, Trecsall, Trexell, Texall, Trexhal, Trxall, Trezall, Trexxal, Methotrexet, Methotroxate, Methotrexiat, Methotrexate, Methotrexite, Methotrxate, Methotrecate, Methotrexat, Methrotrexate, Methotrexte, Methotexate, Methrotexate, Methotreaxate, Methotrexade, Methotrxet.

FAQ

1. What is Methotrexate (Rheumatrex) and what is it used for?
Methotrexate is a medical drug available to us under the name rheumatrex which belongs to a class of medication called antimetabolites. This medicine is used to treat several kinds of cancers including head, neck, lungs, uterus, breast and skin including psoriasis.

2. When and how to use Methotrexate?
Methotrexate is available to us in a form of pill that must be taken by mouth with or without food as per your doctor's prescription. For psoriasis, take it once every week. The dosage and length of the treatment is based on your medical condition, response to the treatment and other medicine that you may be taking for the same or different reason. Swallow the tablet whole rather than chewing or crushing it in your mouth as it may release all the drug in your mouth which increases the risk of side effects. Your doctor may start you with a low dose which will increase gradually. Do not increase your dose or take it more often than prescribed as this may also increase the risk of side effects without any improvement in your condition. Discuss all the other medicines that you might be taking along with Methotrexate for the same or different reasons. Follow the medical prescription carefully and inform your doctor in case of any exception or confusion.

3. What are the side effects of Methotrexate?
Common side effects observed while medicating with Methotrexate are dizziness, drowsiness, nausea, stomach pain or vomiting may occur. Inform your doctor if these conditions persist or get worse. There are some serious side effects which must be informed to the doctor right away if observed such as mouth sores, diarrhea, signs of anemia(unusual tiredness, pale skin), signs of liver problem (dark urine, persistent nausea/vomiting, stomach/abdominal pain, yellowing eyes/skin), easy bruising/bleeding, black stools, enlarged glands/lymph nodes, bone pain, unusual pain and discoloration of the skin, signs of kidney problems (change in the amount of urine), dry cough, muscle weakness, signs of infection etc. There are also some severe allergic reactions involved with these medications which require immediate medical attention if observed such as rash, itching/swelling (especially of the face/tongue/throat), trouble breathing, severe dizziness, weakness on one side of the body, neck stiffness, severe headache, vision changes, irregular heartbeat, mental/mood changes, seizures etc.

4. Is Methotrexate safe during pregnancy?
Methotrexate is a kind of medicine that is generally not recommended to be used during pregnancy. The effects involved in this medication includes craniofacial abnormalities, defects in limbs CNS defects etc. Consult your doctor before using this medicine if you are pregnant or planning to get pregnant.

5. How long does Methotrexate take to work?
Methotrexate is a kind of medicine that takes a long time to deliver and improve your condition. As soon as your dose is scheduled with maximum power, you may notice improvement in your condition no sooner than 12 weeks of scheduled medication. You may not feel any change or different but the medicine will be doing its job.