Generic Viagra® : SILDENAFIL CITRATE
Sildenafil Citrate is the chemical name of the active ingredient in Viagra®
Viagra® is the registered trademark of Pfizer Inc.
Generic Buy Viagra ™ 200 mg for erectile dysfunction
Buy online Generic Viagra (tm) 200mg (10 Pills), Viagra Cost, Price $32.00 at 62.88% Discount.
- Helps you achieve erections!
- Starts working in as little as 30 minutes!
- Prescribed to more than 16 million men worldwide!
- Improves erections in 4 out of 5 males!
High dose sildenafil citrate as a salvage therapy for severe erectile dysfunction
| http://www.nature.com/ijir/journal/v14/n6/full/3900936a.html |
 |
| C G McMahon |
|
|
Australian Centre for Sexual Health, St. Luke's Hospital Complex, Sydney, Australia
|
|
Correspondence to: CG McMahon, Australian Centre for Sexual Health, St. Luke's Hospital Complex, Hemsley House, 20 Roslyn Street, Potts Point, NSW, Australia 2011. E-mail: cmcmahon@mail.usyd.edu.au
The objectives of this study were to evaluate the efficacy and tolerability of high dose sildenafil as a salvage therapy for patients refractory to the maximum recommended dose of sildenafil. Fifty four fully evaluated patients with chronic erectile failure (ED) who had previously failed to respond to a home trial of sildenafil (100 mg) with erections suitable for sexual intercourse were studied. Each man was treated at home with sildenafil at escalating doses of up to 200 mg until either maximal response or intolerable adverse effects occurred. Erectile function was quantified using the erectile function domain of the International Index of Erectile Function (IIEF) before treatment, with sildenafil 100 mg and with maximal dose of sildenafil and a global efficacy question after 4 weeks of treatment.
The mean age of the study group was 59.6±11.2 y. 13/54 (24%) had arteriogenic ED, 16/54 (30%) had mixed vasculogenic ED, 9/54 (17%) had cavernosal veno-occlusive dysfunction, 11/54 (20%) had post radical retropubic prostatectomy ED and 5/54 (9%) had psychogenic ED. 13/54 (24.1%) responded to sildenafil at a median maximal dose of 200 mg, 4/13 required 150 mg and 9/13 required 200 mg. 41/54 (76%) failed to respond to sildenafil. Mean IIEF question 3 and 4 scores were 1.5 and 1.4 at baseline, 2.2 and 1.9 with sildenafil 100 mg, 2.8 and 2.5 with sildenafil 150 mg and 3.0 and 2.9 with sildenafil 200 mg, respectively. After 4 weeks, treatment was regarded as having improved their erections by 37%, 46.3% and 68% of patients with sildenafil 100 mg, 150 mg and 200 mg, respectively. 34/54 (63%) reported adverse effects with maximal dose sildenafil comprising headache (19), facial flushing (32), dyspepsia (14), nasal congestion (11), dizziness (5) and visual disturbances (5). 4/13 (31%) responders refused to continue treatment due to adverse effects.
In conclusion, sildenafil at doses of up to 200 mg is an effective salvage therapy for 24.1% of previous sildenafil non-responders but is limited by a significantly higher incidence of adverse effects and a 31% treatment discontinuation rate.
|
Viagra™ DRUG INFO
IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you.
SILDENAFIL - ORAL (sill-DEN-uh-fil)
COMMON BRAND NAME(S): Viagra™
Vyagra is a common misspelling of Viagra (sildenafil). Kamagra Silagra Edegra Penegra Zenegra Manforce Cenforce Neogra Vigore
USES OF SILDENAFIL:
Sildenafil is used to treat male sexual function problems (impotence or erectile dysfunction-ED). In combination with sexual stimulation, sildenafil works by increasing blood flow to the penis to help a man get and keep an erection.This drug does not protect against sexually transmitted diseases (such as HIV, hepatitis B, gonorrhea, syphilis). Practice "safe sex" such as using latex condoms. Consult your doctor or pharmacist for more details.
BEFORE USING SILDENAFIL:
Before taking sildenafil, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
HOW TO USE SILDENAFIL:
To treat erectile dysfunction-ED, take this drug by mouth as directed by your doctor, usually as needed. Take sildenafil at least 30 minutes, but no more than 4 hours, before sexual activity (1 hour before is the most effective). Do not take more than once daily.
A high-fat meal may delay how quickly the drug begins to work.
The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Tell your doctor if your condition does not improve.
SIDE EFFECTS OF SILDENAFIL:
Headache, flushing, stomach upset, nasal stuffiness, diarrhea and dizziness might occur. If these effects persist or worsen, notify your doctor promptly. Unlikely but report promptly: painful or other urination problems, vision problems, skin rash. Very unlikely but report promptly: chest pain, fainting, foot or ankle swelling. If you experience a painful or prolonged erection (lasting longer than 4 hours), stop using this drug and seek immediate medical attention. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS WHEN USING SILDENAFIL:
Before using this drug, tell your doctor your medical history, including: allergies (especially drug allergies), penis conditions such as fibrosis/scarring (e.g., Peyronie's disease), history of painful/prolonged erection (priapism), sickle cell anemia, blood system cancers (such as leukemia or myeloma), eye problems (retina diseases), kidney or liver disease, bleeding disorders, active stomach ulcers, heart disease, stroke, very high or low blood pressure. Limit alcohol intake, as it may aggravate side effects of this drug. Since this drug may cause dizziness, caution is advised when performing tasks requiring alertness (e.g., driving). To avoid dizziness and lightheadedness when rising from a seated or lying position, get up slowly. This drug is not to be used in women or children. The elderly may be more sensitive to the side effects of this drug, therefore caution is advised in this group.
DRUG INTERACTIONS OF SILDENAFIL:
Tell your doctor of all nonprescription and prescription medication you may use, especially of: nitrate medications (e.g., nitroglycerin, isosorbide dinitrate), nitroprusside (any "nitric oxide donor" medicines), cimetidine, erythromycin, azole antifungals (e.g., itraconazole, ketoconazole), mibefradil, rifamycins (e.g., rifampin), high blood pressure medicines, certain HIV protease inhibitors (such as saquinavir, ritonavir, amprenavir), delavirdine. Do not start or stop any medicine without doctor or pharmacist approval.
OVERDOSE OF SILDENAFIL:
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include severe dizziness, fainting, or prolonged erection.
NOTES On SILDENAFIL:
Do not share this medication with others, since they may have a problem that is not effectively treated by this drug. Use of this drug does not protect against sexually transmitted diseases (e.g., HIV, Hepatitis B, gonorrhea, syphilis)
MISSED DOSE OF SILDENAFIL:
Not applicable.
STORAGE OF SILDENAFIL:
Store at room temperature between 59 and 86 degrees F (15-30 degrees C) away from light and moisture.
COST OF SILDENAFIL:
The lowest MyGenericPharmacy.com price for the most common version of Viagra (sildenafil) is around $3.20, 62.88% off the average online retailing price of $86.20.
Generic Viagra® : SILDENAFIL CITRATE
Sildenafil Citrate is the chemical name of the active ingredient in Viagra®
Viagra® is the registered trademark of Pfizer Inc.
Generic Buy Viagra ™ 200 mg for erectile dysfunction
Buy online Generic Viagra (tm) 200mg (10 Pills), Viagra Cost, Price $32.00 at 62.88% Discount.
- Helps you achieve erections!
- Starts working in as little as 30 minutes!
- Prescribed to more than 16 million men worldwide!
- Improves erections in 4 out of 5 males!
High dose sildenafil citrate as a salvage therapy for severe erectile dysfunction
| http://www.nature.com/ijir/journal/v14/n6/full/3900936a.html |
|
| C G McMahon |
|
|
Australian Centre for Sexual Health, St. Luke's Hospital Complex, Sydney, Australia
|
|
Correspondence to: CG McMahon, Australian Centre for Sexual Health, St. Luke's Hospital Complex, Hemsley House, 20 Roslyn Street, Potts Point, NSW, Australia 2011. E-mail: cmcmahon@mail.usyd.edu.au
The objectives of this study were to evaluate the efficacy and tolerability of high dose sildenafil as a salvage therapy for patients refractory to the maximum recommended dose of sildenafil. Fifty four fully evaluated patients with chronic erectile failure (ED) who had previously failed to respond to a home trial of sildenafil (100 mg) with erections suitable for sexual intercourse were studied. Each man was treated at home with sildenafil at escalating doses of up to 200 mg until either maximal response or intolerable adverse effects occurred. Erectile function was quantified using the erectile function domain of the International Index of Erectile Function (IIEF) before treatment, with sildenafil 100 mg and with maximal dose of sildenafil and a global efficacy question after 4 weeks of treatment.
The mean age of the study group was 59.6±11.2 y. 13/54 (24%) had arteriogenic ED, 16/54 (30%) had mixed vasculogenic ED, 9/54 (17%) had cavernosal veno-occlusive dysfunction, 11/54 (20%) had post radical retropubic prostatectomy ED and 5/54 (9%) had psychogenic ED. 13/54 (24.1%) responded to sildenafil at a median maximal dose of 200 mg, 4/13 required 150 mg and 9/13 required 200 mg. 41/54 (76%) failed to respond to sildenafil. Mean IIEF question 3 and 4 scores were 1.5 and 1.4 at baseline, 2.2 and 1.9 with sildenafil 100 mg, 2.8 and 2.5 with sildenafil 150 mg and 3.0 and 2.9 with sildenafil 200 mg, respectively. After 4 weeks, treatment was regarded as having improved their erections by 37%, 46.3% and 68% of patients with sildenafil 100 mg, 150 mg and 200 mg, respectively. 34/54 (63%) reported adverse effects with maximal dose sildenafil comprising headache (19), facial flushing (32), dyspepsia (14), nasal congestion (11), dizziness (5) and visual disturbances (5). 4/13 (31%) responders refused to continue treatment due to adverse effects.
In conclusion, sildenafil at doses of up to 200 mg is an effective salvage therapy for 24.1% of previous sildenafil non-responders but is limited by a significantly higher incidence of adverse effects and a 31% treatment discontinuation rate.
|
Viagra™ DRUG INFO
IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you.
SILDENAFIL - ORAL (sill-DEN-uh-fil)
COMMON BRAND NAME(S): Viagra™
Vyagra is a common misspelling of Viagra (sildenafil). Kamagra Silagra Edegra Penegra Zenegra Manforce Cenforce Neogra Vigore
USES OF SILDENAFIL:
Sildenafil is used to treat male sexual function problems (impotence or erectile dysfunction-ED). In combination with sexual stimulation, sildenafil works by increasing blood flow to the penis to help a man get and keep an erection.This drug does not protect against sexually transmitted diseases (such as HIV, hepatitis B, gonorrhea, syphilis). Practice "safe sex" such as using latex condoms. Consult your doctor or pharmacist for more details.
BEFORE USING SILDENAFIL:
Before taking sildenafil, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
HOW TO USE SILDENAFIL:
To treat erectile dysfunction-ED, take this drug by mouth as directed by your doctor, usually as needed. Take sildenafil at least 30 minutes, but no more than 4 hours, before sexual activity (1 hour before is the most effective). Do not take more than once daily.
A high-fat meal may delay how quickly the drug begins to work.
The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Tell your doctor if your condition does not improve.
SIDE EFFECTS OF SILDENAFIL:
Headache, flushing, stomach upset, nasal stuffiness, diarrhea and dizziness might occur. If these effects persist or worsen, notify your doctor promptly. Unlikely but report promptly: painful or other urination problems, vision problems, skin rash. Very unlikely but report promptly: chest pain, fainting, foot or ankle swelling. If you experience a painful or prolonged erection (lasting longer than 4 hours), stop using this drug and seek immediate medical attention. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS WHEN USING SILDENAFIL:
Before using this drug, tell your doctor your medical history, including: allergies (especially drug allergies), penis conditions such as fibrosis/scarring (e.g., Peyronie's disease), history of painful/prolonged erection (priapism), sickle cell anemia, blood system cancers (such as leukemia or myeloma), eye problems (retina diseases), kidney or liver disease, bleeding disorders, active stomach ulcers, heart disease, stroke, very high or low blood pressure. Limit alcohol intake, as it may aggravate side effects of this drug. Since this drug may cause dizziness, caution is advised when performing tasks requiring alertness (e.g., driving). To avoid dizziness and lightheadedness when rising from a seated or lying position, get up slowly. This drug is not to be used in women or children. The elderly may be more sensitive to the side effects of this drug, therefore caution is advised in this group.
DRUG INTERACTIONS OF SILDENAFIL:
Tell your doctor of all nonprescription and prescription medication you may use, especially of: nitrate medications (e.g., nitroglycerin, isosorbide dinitrate), nitroprusside (any "nitric oxide donor" medicines), cimetidine, erythromycin, azole antifungals (e.g., itraconazole, ketoconazole), mibefradil, rifamycins (e.g., rifampin), high blood pressure medicines, certain HIV protease inhibitors (such as saquinavir, ritonavir, amprenavir), delavirdine. Do not start or stop any medicine without doctor or pharmacist approval.
OVERDOSE OF SILDENAFIL:
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include severe dizziness, fainting, or prolonged erection.
NOTES On SILDENAFIL:
Do not share this medication with others, since they may have a problem that is not effectively treated by this drug. Use of this drug does not protect against sexually transmitted diseases (e.g., HIV, Hepatitis B, gonorrhea, syphilis)
MISSED DOSE OF SILDENAFIL:
Not applicable.
STORAGE OF SILDENAFIL:
Store at room temperature between 59 and 86 degrees F (15-30 degrees C) away from light and moisture.
COST OF SILDENAFIL:
The lowest MyGenericPharmacy.com price for the most common version of Viagra (sildenafil) is around $3.20, 62.88% off the average online retailing price of $86.20.
FAQ
1. Viagra samples
If you want to try Viagra and you don't want to buy 30 or 60 pills pack so you can order trial pack of just 10 pills and it is available on mygenericpharmacy.com you will receive it in just 7 to 12 days. Try it if you satisfied with the product then you can order for more.
2. Cialis samples
If you want to try Cialis and you don’t want to buy 30 or 60 pills pack so you can order trial pack of just 10 pills and it is available on mygenericpharmacy.com you will receive it in just 7 to 12 days. Try it if you satisfied with the product then you can order for more.
3. Levitra samples
If you want to try Levitra and you don’t want to buy 30 or 60 pills pack so you can order trial pack of just 10 pills and it is available on mygenericpharmacy.com you will receive it in just 7 to 12 days. Try it if you satisfied with the product then you can order for more.
