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About Generic Tobi® (Tobramycin)

Key Details

1. Generic Tobi™ 0.03% 10 ml for Eye Care
2. Buy online Generic Tobi™ 0.03 % 10ml (3 Bottles), Tobi Cost, Price $10.50 at 75% Discount
3. Targets Pseudomonas aeruginosa effectively
4. Improves lung function in cystic fibrosis patients
5. Reduces frequency of lung infections

How Generic Tobi Works

Generic Tobi contains tobramycin, an aminoglycoside antibiotic that works by binding to the 30S subunit of bacterial ribosomes, disrupting protein synthesis. This interference causes the production of defective proteins, leading to bacterial cell death. When administered via inhalation, tobramycin reaches very high concentrations directly in the airways, making it highly effective against Pseudomonas aeruginosa, the most common chronic pathogen in cystic fibrosis patients.

Because Tobi is inhaled rather than taken orally or intravenously, systemic absorption is minimal, which significantly reduces the risk of kidney toxicity and hearing damage commonly associated with aminoglycosides. The medication is used in 28-day on / 28-day off cycles to reduce bacterial load, improve lung function, and slow disease progression while minimizing bacterial resistance. Regular monitoring ensures safe long-term use.

Drug Info

TOBRAMYCIN– ORAL (toe-bra-MY-sin)
Common Brand Name(s): Tobi™

Other name brands for this medication
Toba, Nebcin, Tocin, Tobastar, Obra

Uses of Tobi

Ophthalmic tobramycin is used in the eye to treat bacterial infections of the eye. Tobramycin works by killing bacteria.

Ophthalmic tobramycin may be used alone or with other medicines for eye infections. Either the drops or the ointment form of this medicine may be used alone during the day. In addition, both forms may be used together, with the drops being used during the day and the ointment at night. Tobramycin ophthalmic preparations are available only with your doctor's prescription.

Before Using Tobi

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

How to Use Tobi

For patients using tobramycin ophthalmic solution (eye drops):

·  The bottle is only partially full to provide proper drop control.

·  To use:

First, wash your hands. Tilt the head back and with the index finger of one hand, press gently on the skin just beneath the lower eyelid and pull the lower eyelid away from the eye to make a space. Drop the medicine into this space. Let go of the eyelid and gently close the eyes. Do not blink. Keep the eyes closed for 1 or 2 minutes, to allow the medicine to come into contact with the infection. If you think you did not get the drop of medicine into your eye properly, use another drop.

To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). Also, keep the container tightly closed. If your doctor ordered two different ophthalmic solutions to be used together, wait at least 5 minutes between the times you apply the medicines. This will help to keep the second medicine from ``washing out'' the first one.

Side Effects of Tobi

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Eye ointments usually cause your vision to blur for a few minutes after application. Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Precautions

If your eye infection does not improve within a few days, or if it becomes worse, check with your doctor.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Amifampridine

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Alcuronium
Atracurium
Cidofovir
Cisatracurium
Colistimethate Sodium
Decamethonium
Doxacurium
Ethacrynic Acid
Fazadinium
Foscarnet
Furosemide
Gallamine
Hexafluorenium
Lysine
Mannitol
Metocurine
Mivacurium
Pancuronium
Pipecuronium
Rapacuronium
Rocuronium
Succinylcholine
Tacrolimus
Tubocurarine
Vancomycin
Vecuronium
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Overdose

If overdose is suspected, contact a poison control center or emergency room immediately.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Cost of Tobi

The lowest MyGenericPharmacy.com price for the most common version of Tobi (Tobramycin) is around $3.50, 75% off the average online retailing price of $42.00.

What is Tobi / Tobramycin?
Tobi is an inhaled antibiotic containing tobramycin used to manage chronic Pseudomonas aeruginosa lung infections in cystic fibrosis patients. It delivers medication directly to the lungs for targeted treatment.

How Does Tobi Work?
Tobramycin binds to bacterial ribosomes, blocking protein synthesis. This causes bacterial death and reduces lung infection burden.

Benefits of Tobi

1. Targets Pseudomonas aeruginosa effectively
2. Improves lung function in cystic fibrosis patients
3. Reduces frequency of lung infections
4. Direct delivery to lungs → fewer systemic side effects
5. Can be used long-term in on–off cycles
6. Proven to slow disease progression in CF

Dosage & How to Use
Inhalation Solution

1. 300 mg twice daily via nebulizer
2. Use for 28 days ON, then 28 days OFF
3. Inhale doses about 12 hours apart

Inhalation Powder (Podhaler)

1. 112 mg (4 capsules) twice daily
2. Same 28-day on / 28-day off cycle

Important:

1. Use after bronchodilators and airway clearance therapy
2. Do not mix with other nebulized medicines
3. Clean nebulizer properly after each use

Side Effects & Precautions
Common side effects may include:

1. Cough
2. Hoarseness or voice changes
3. Throat irritation
4. Bad taste

Precautions:

1. Baseline and periodic hearing tests recommended
2. Use caution in kidney disease
3. Monitor lung function
4. Stop and report wheezing or breathing difficulty

Who Should Not Take Tobi

1. Allergy to tobramycin or aminoglycosides
2. Severe hearing impairment (use with caution)
3. Myasthenia gravis (use with caution)
4. Pregnancy: use only if benefits outweigh risks

Additional information :
DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.

MISSPELLINGS OF TOBA :
Toby, Tobii, Tobi medication, Tobie, Tobai, Tobii inhaler, Tobii medication, Tobi inhaler, Tobie inhaler, Toibi, Tobii antibiotic, Tobi antibiotic, Tobramisin, Tobramicin, Tobramycin, Tobramysin, Tobramisin, Tobramysine, Tobramycin inhaler, Tobramicin inhaler, Tobramycen, Tobramicin eye drops, Tobramysin eye drops, Tobramycine.

FAQ

1. What is Tobramycin (Toba) and what is it used for?
Tobramycin is a medical drug solution available to us under the name Toba which belongs to a class of medication called Antibiotics. This medicine used to treat infection caused in the eye by killing the bacteria responsible for causing infection. However, it does not treat a viral or any fungal infection.

2. When and how to use Tobramycin?
Tobramycin is available to us in a form of eye drop solution that must be used in the eye as per your doctor's prescription. Tilt your head back and drop the solution by pulling your eyelid down to make a pouch. If using a contact lens, wait for at least 15 minutes after dropping the medicine in the eye. You must close your eyes for at least 1-2 minute after dropping the solution. Do not touch the dropper or let it touch any surface to avoid contamination. You may replace the dropper cap after each use rather than washing it. Put a gap of at least 15 minutes if you are using any other eye solution for the same or different reason. Try not to blink or rub your eye. Take the medicine at the same time daily to get the most benefits from it. Follow the medical guide carefully and consult your doctor in case of any confusion or doubts.

3. What are the side effects of Tobramycin?
Common side effects observed while medicating with Tobramycin are redness in the eye, tearing, eye discomfort or swelling/itching in eyelids may occur. Inform your doctor if these conditions persist or get worse. There are some severe allergic reactions involved with these medications which require immediate medical attention if observed such as rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing etc.

4. Is Tobramycin an effective medicine?
The formulation of Tobramycin was found to be highly effective as a precautionary medication. It is effective in stopping or killing the bacteria causing infection in the eyes. Also its effectiveness is significantly reduced if used for any other kind of infection or used unnecessarily.

5. How long should Tobramycin be used?
Tobramycin is a kind of medicine that is used for a short term duration i.e. it must be used twice a day for seven days or according to your doctor guidance and prescription. You vision may get blurred after using this medicine. Inform your doctor if you condition does not improve within the meantime.

6. Is tobramycin better than cyclosporine?
Both Tobramycin and cyclosporine are considered as an effective medicine to treat dryness of the eye. However when compared, cyclosporine produced better and greater improvements in tear breakup time and Schirmer's score(Tear production by eye to keep it moist) than Tobramycin after 12 weeks of examined treatment.

7. How long does it take tobramycin to work?
This medication need to begin having results inside one to two hours; however, you may now not see the results of this medication outwardly.

8. What bacteria does tobramycin kill?
Tobramycin has a narrow spectrum of hobby and is energetic in opposition to Gram-fine Staphylococcus aureus and various Gram-negative micro organism. Clinically, tobramycin is regularly used to cast off Pseudomonas aeruginosa in cystic fibrosis patients.